Protein Alignment myd and Sdf4

DIOPT Version :10

• Sequence 1: NP_732406.1
• Gene: myd / 42303
• FlyBaseID: FBgn0051475
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_035471.1
• Gene: Sdf4 / 20318
• MGIID: 108079
• Length: 361
• Species: Mus musculus
• Alignment Length: 420
• Identity: 116/420 - (27%)
• Similarity: 197/420 - (46%)
• Gaps: 75/420 - (17%)

  Fly    13 WL-----RCSTLCAILFY-MFFIGLILHSTSQKLQQQLKEQGTSSSSSSSSSSSSSSSSSSSSST 71
            ||     |.|:||.:..: ::|:||:|                  ...:::..::.||:...::.
Mouse     3 WLVAMTPRQSSLCGLAAHGLWFLGLVL------------------LMDATARPANHSSTRERAAN 49

  Fly    72 QADTKMAPNVGHNGAQRWPNTLQELEQQQQK--HEQSMRLQPVANNLDSRNENNHRQPHPQSQKV 134
            :.:.::.|....||.:      .|::....|  |::..    :..::|..:|::  :|....:|
Mouse    50 REENEIMPPDHLNGVK------LEMDGHLNKDFHQEVF----LGKDMDGFDEDS--EPRRSRRK- 101

  Fly   135 QNASKSPNQPETVILAASNVNEKQILAKAFKRADRSRDGILSIQELGQYINRRIVEHIDEAIMNN 199
                                     |...|.:.|.:.|..:|.:|:..:|..:..||..||:..|
Mouse   102 -------------------------LMVIFSKVDVNTDRRISAKEMQHWIMEKTAEHFQEAVKEN 141

  Fly   200 AREFRRVDIGPADGLITWDEYHRFFLREHGMTEADIDE----HDEIRHTALNRRAREDMMRDKAR 260
            ...||.|| ...||.::||||...||...|..|.:|.|    |:|::   ::...:|.:...:.|
Mouse   142 KLHFRAVD-PDGDGHVSWDEYKVKFLASKGHNEREIAEAIKNHEELK---VDEETQEVLGNLRDR 202

  Fly   261 WSEAAR--TDLFTLTIDEYLSFRHPESSVSNLLELVDDLLRQFDQDGDDQLTLEEFSDLNVDDDD 323
            |.:|..  .||. ||.||:|||.|||.|...|..:|.::.|..|||||.||:|.||..|.|...:
Mouse   203 WYQADNPPADLL-LTEDEFLSFLHPEHSRGMLKFMVKEIFRDLDQDGDKQLSLPEFISLPVGTVE 266

  Fly   324 DLMRKSLISKTLVERREEFKRIIDKNHDGKADRGELLNYVNPKTPRYALQEAATLFSLCDENKDE 388
            :...:.:....:.:|::||:.:||.||||.....||.||::|.....||.||..:.::.|||::.
Mouse   267 NQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTMEELENYMDPMNEYNALNEAKQMIAIADENQNH 331

  Fly   389 LLTLKEMTDHAEIFLQSKMIDTANSFHTEF 418
            .|..:|:..::|.|..||::|.|.:.|.||
Mouse   332 HLEPEEILKYSEFFTGSKLMDYARNVHEEF 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myd	NP_732406.1	EFh_CREC	160..403	CDD:330175	86/248 (35%)
		EF-hand motif	160..188	CDD:320023	7/27 (26%)
		EF-hand motif	198..228	CDD:320023	13/29 (45%)
		EF-hand motif	256..285	CDD:320023	14/30 (47%)
		EF-hand motif	293..322	CDD:320023	14/28 (50%)
		EF-hand motif	338..367	CDD:320023	14/28 (50%)
		EF-hand motif	374..403	CDD:320023	8/28 (29%)
Sdf4	NP_035471.1	EFh_CREC_cab45	66..346	CDD:320023	93/316 (29%)
		EF-hand motif	66..94	CDD:320023	5/33 (15%)
		EF-hand motif	101..130	CDD:320023	8/54 (15%)
		EF-hand motif	140..169	CDD:320023	13/29 (45%)
		EF-hand motif	198..228	CDD:320023	14/30 (47%)
		EF-hand motif	236..265	CDD:320023	14/28 (50%)
		EF-hand motif	281..310	CDD:320023	14/28 (50%)
		Necessary for intracellular retention in Golgi apparatus lumen	308..361		17/52 (33%)
		EF-hand motif	317..346	CDD:320023	8/28 (29%)