DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31475 and H10E21.4

DIOPT Version :9

Sequence 1:	NP_001262725.1	Gene:	CG31475 / 42303	FlyBaseID:	FBgn0051475	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_497128.1	Gene:	H10E21.4 / 175168	WormBaseID:	WBGene00019184	Length:	236	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	61/262 - (23%)
Similarity:	96/262 - (36%)	Gaps:	82/262 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 AFKRADRSRDGILSIQELGQYINRRIVEHIDEAIMNNAREFRRVDIGPADGLITWDEY-HRFFLR 226
            :|...|.:.||.||.:||..::.:|                     |..||    .|| .||.|.
Worm    22 SFDLVDANNDGKLSEKELITFMRKR---------------------GRPDG----QEYFQRFDLD 61

  Fly   227 EHG-------------MTEADID-EHDEIRHTALNRRAREDMMRDKARWSEAARTDLFTLTIDEY 277
            .:|             |:...:| :::..:...||    :|.:.|||. .|..|.|
Worm    62 RNGHLDISEFVPLVYEMSRRPVDMDYEFFKKMDLN----DDGIVDKAE-VEKIRKD--------- 112

  Fly   278 LSFRHPESSVSNLLELVDDLLRQFDQDGDDQLTLEEFSDLNVDDDDDLMRKSLISKTLVERREEF 342
                       |...::|.:|...|.:.|.|||..||.:          ..|..:|:|....|:.
Worm   113 -----------NNDRIIDGILSIADTNRDGQLTYAEFKN----------HLSSGAKSLSPAEEQR 156

  Fly   343 KR------IIDKNHDGKADRGELLNY-VNPKTPRYALQEAATLFSLCDENKDELLTLKEMTDHAE 400
            .:      .||.|.|.|.|:.||..: ....|.:....:...:|::.|:|:|..||..|:...|:
Worm   157 NQALQLLSFIDANGDNKLDQLELYTFSQKTSTNKVTKSDVQQIFAMLDKNQDGYLTENELLQLAQ 221

  Fly   401 IF 402
            .|
Worm   222 QF 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31475	NP_001262725.1	EF-hand_7	160..224	CDD:290234	15/61 (25%)
		EF-hand_7	296..363	CDD:290234	20/73 (27%)
		EFh	301..360	CDD:298682	18/64 (28%)
		EFh	344..398	CDD:298682	16/60 (27%)
H10E21.4	NP_497128.1	EF-hand_7	21..75	CDD:290234	18/77 (23%)
		EFh	23..72	CDD:238008	18/73 (25%)
		EF-hand_7	87..139	CDD:290234	18/76 (24%)
		EFh	88..143	CDD:298682	19/89 (21%)
		EF-hand_7	161..219	CDD:290234	16/57 (28%)
		EFh	166..221	CDD:238008	16/54 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910