Protein Alignment myd and Calu

DIOPT Version :10

• Sequence 1: NP_732406.1
• Gene: myd / 42303
• FlyBaseID: FBgn0051475
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_031620.1
• Gene: Calu / 12321
• MGIID: 1097158
• Length: 315
• Species: Mus musculus
• Alignment Length: 326
• Identity: 88/326 - (26%)
• Similarity: 143/326 - (43%)
• Gaps: 51/326 - (15%)

  Fly   116 LDSRNENNHRQPH-PQ-SQKVQNASKSPNQPETVILAASNV---------NEKQILAKAFKRADR 169
            |....|...|..| || |.||.|.:::.:......|.|...         ..|:.|.|...:.|.
Mouse    18 LSKPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFDQLTPEESKERLGKIVSKIDD 82

  Fly   170 SRDGILSIQELGQYI----NRRIVEHIDEAIMNNAREFRRVDIGPADGLITWDEYHRFFLREHGM 230
            .:||.:::.||..:|    .|.|.|.::       |:::..|:. .|||::|:||..   ..:|.
Mouse    83 DKDGFVTVDELKGWIKFAQKRWIHEDVE-------RQWKGHDLN-EDGLVSWEEYKN---ATYGY 136

  Fly   231 TEADIDEHDEIRHTALNRRAREDMMRDKARWSEAARTDLFTLTIDEYLSFRHPESSVSNLLELVD 295
            ...|.|..|...:       ::.|:||:.|:..|.:......|.:|:.:|.|||........:|.
Mouse   137 VLDDPDPDDGFNY-------KQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQ 194

  Fly   296 DLLRQFDQDGDDQLTLEEF------SDLNVDDDDDLMRKSLISKTLVERREEFKRIIDKNHDGKA 354
            :.:...|::.|..:.|||:      .|.|.|:.:.:       ||   .||:|....|||.|||.
Mouse   195 ETMEDIDKNADGFIDLEEYIGDMYSHDGNADEPEWV-------KT---EREQFVEFRDKNRDGKM 249

  Fly   355 DRGELLNYVNPKTPRYALQEAATLFSLCDENKDELLTLKEMTDHAEIFLQSKMIDTANSF--HTE 417
            |:.|..:::.|....:|..||..|....|:|||..||.:|:.|..::|:.|:..|...:.  |.|
Mouse   250 DKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDE 314

  Fly   418 F 418
            |
Mouse   315 F 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myd	NP_732406.1	EFh_CREC	160..403	CDD:330175	69/252 (27%)
		EF-hand motif	160..188	CDD:320023	9/31 (29%)
		EF-hand motif	198..228	CDD:320023	8/29 (28%)
		EF-hand motif	256..285	CDD:320023	9/28 (32%)
		EF-hand motif	293..322	CDD:320023	9/34 (26%)
		EF-hand motif	338..367	CDD:320023	12/28 (43%)
		EF-hand motif	374..403	CDD:320023	11/28 (39%)
Calu	NP_031620.1	EFh_CREC_Calumenin	37..299	CDD:320026	76/289 (26%)
		EF-hand motif	37..66	CDD:320026	5/28 (18%)
		EF-hand motif	72..101	CDD:320026	8/28 (29%)
		EF-hand motif	108..137	CDD:320026	9/39 (23%)
		EF-hand motif	155..184	CDD:320026	9/28 (32%)
		EF-hand motif	192..221	CDD:320026	6/28 (21%)
		EF-hand motif	233..262	CDD:320026	12/28 (43%)
		EF-hand motif	269..299	CDD:320026	12/29 (41%)
		Prevents secretion from ER	312..315		1/2 (50%)