Protein Alignment CG5555 and ETP1

DIOPT Version :9

• Sequence 1: NP_001262724.1
• Gene: CG5555 / 42302
• FlyBaseID: FBgn0038686
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_011853.1
• Gene: ETP1 / 856376
• SGDID: S000001002
• Length: 585
• Species: Saccharomyces cerevisiae
• Alignment Length: 523
• Identity: 165/523 - (31%)
• Similarity: 258/523 - (49%)
• Gaps: 122/523 - (23%)

  Fly   132 GLIHLYK-KNERKAIKE-------APSNQLCLLAVPATLNCHDLLNFIAP---CHAEIKHIQIVR 185
            |:|.|:| .|....:.|       .....:|:|.||.....||||:|...   .:.::.:.:|:|
Yeast    86 GIIRLFKLSNANNTLNEKEILTIPGDDTMICILFVPTYFTVHDLLHFYIGDDIVNKQVSNFRILR 150

  Fly   186 D---GSPNQFMVLLEFRSNESALEFYKSYNGSTYNSLEPDSLCHAVWVSEV--ERSEHGAPPMGH 245
            :   |....|.||::||:...|..|.:.:||.:::.::|:: ||.:.|.|:  ::.....|....
Yeast   151 NQQKGMGFNFTVLIKFRNALDAKNFKEEFNGKSFSRMDPET-CHVISVKEIVFQKKLFQRPAANE 214

  Fly   246 --------------------TELPTCPVCLERMDESVDGVLTILCNHAFHASCLMKWGDSTCPVC 290
                                .|||||||||||||....|::||.|.|.||..||.||.:|.||||
Yeast   215 DFPYLLTDPFTVKKKKELVKVELPTCPVCLERMDSETTGLVTIPCQHTFHCQCLNKWKNSRCPVC 279

  Fly   291 RH----VQTPGLVE---DSV-CMECEGTDSLWICLICGHVGCGRYQGGHAAAHFRATNHTFAMQL 347
            ||    :....|::   ||. |..|..||:||||||||:||||||...||..|:..|.|.|||.:
Yeast   280 RHSSLRLSRESLLKQAGDSAHCATCGSTDNLWICLICGNVGCGRYNSKHAIKHYEETLHCFAMDI 344

  Fly   348 GTSSVWDYAGDNFVHRLFQNKSDGKLVASQTEKDEREEKI---DSMQ------------------ 391
            .|..||||||||:||||.||:.|||||......|:....|   |.:|
Yeast   345 RTQRVWDYAGDNYVHRLVQNEVDGKLVEVGGSGDDDNNDIGNSDELQNVVYGNRSKNGEKSNSNK 409

  Fly   392 ----------------MEFTYLLTSQLDTQRKYYEERMERLEQEWQNHKATANDAKTEVSELQQL 440
                            :|:..:|.|||::||:|||.:::..:|       ||:|:    |.::.|
Yeast   410 KDGELAANFLRHREYHLEYVQVLISQLESQREYYELKLQEKDQ-------TASDS----SNVESL 463

  Fly   441 QQNMQKEKVNLE--------RKLAQHTAKLKDVQKQLNEERELSKALQSNQSSWHGKYKLLEQQY 497
            :::|:..|:..:        |::||        :.:|.|:..:.:.||:|......|.:.||::.
Yeast   464 KKSMEDLKLQFQVTQKEWQKREMAQ--------KSKLEEDMLVIEGLQANLDHLSKKQEQLEREN 520

  Fly   498 NEFKQTHDAEVTELKEQLRDIMFFLDNQQKL--ANTEIAGGTVT-----GIAEKEPDPNTRRRNR 555
            ...:::..    :|:||::|:||:||:|:|.  |:..:..||:.     |.|  :...:.::||:
Yeast   521 KALEESKQ----DLEEQVKDLMFYLDSQEKFKDADESVKEGTILIQQPHGAA--QASKSKKKRNK 579

  Fly   556 RKK 558
            .||
Yeast   580 NKK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5555	NP_001262724.1	RRM_BRAP2	150..234	CDD:241162	26/91 (29%)
		zf-RING_2	249..291	CDD:290367	26/41 (63%)
		zf-UBP	304..363	CDD:280334	36/58 (62%)
		CENP-F_leu_zip	366..517	CDD:287450	43/195 (22%)
		DUF4200	396..517	CDD:290574	31/128 (24%)
ETP1	NP_011853.1	RRM_ETP1	114..201	CDD:410116	26/87 (30%)
		RING-H2_BRAP2	238..281	CDD:319371	27/42 (64%)
		zf-UBP	301..363	CDD:396634	39/61 (64%)
		Smc	409..>534	CDD:224117	31/147 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345729
Domainoid	1	1.000	94	1.000	Domainoid score	I1693
eggNOG	1	0.900	-	-		E1_KOG0804
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4926
Inparanoid	1	1.050	244	1.000	Inparanoid score	I678
Isobase	1	0.950	-	0	Normalized mean entropy	S1679
OMA	1	1.010	-	-		QHG55462
OrthoFinder	1	1.000	-	-		FOG0005004
OrthoInspector	1	1.000	-	-		oto99035
orthoMCL	1	0.900	-	-		OOG6_102472
Panther	1	1.100	-	-	LDO	PTHR24007
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R400
SonicParanoid	1	1.000	-	-		X3020
TreeFam	1	0.960	-	-
	16	15.740