DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and znf362a

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001071201.1	Gene:	znf362a / 777625	ZFINID:	ZDB-GENE-061103-547	Length:	448	Species:	Danio rerio

Alignment Length:	154	Identity:	88/154 - (57%)
Similarity:	113/154 - (73%)	Gaps:	3/154 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 QAKPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRH 218
            :|||:||..|:|:|||:|||:||.|||||:|||.|..|::.|.||||||||.|.||||:||||..
Zfish   279 EAKPHKCPHCTKTFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCLQ 343

  Fly   219 AGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKS 283
            .||.|||:||||||||.|.|..|||:||::||:.:||..:|..|:..|. .|:.|.:.|::||::
Zfish   344 PGCEKAFTQLSNLQSHQRSHNKDKPYKCSNCYRAYSDSASLQIHLSAHA-IKNAKAYCCSMCGRA 407

  Fly   284 YTQETYLQKHLQKH--AEKAEKQQ 305
            ||.||||.||:.||  .|....||
Zfish   408 YTSETYLMKHMSKHTVVEHLVSQQ 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	12/19 (63%)
		zf-H2C2_2	172..197	CDD:290200	15/24 (63%)
		zf-C2H2	186..208	CDD:278523	13/21 (62%)
		C2H2 Zn finger	188..208	CDD:275368	12/19 (63%)
		zf-C2H2_8	191..271	CDD:292531	46/79 (58%)
		zf-H2C2_2	200..227	CDD:290200	19/26 (73%)
		C2H2 Zn finger	216..238	CDD:275368	15/21 (71%)
		C2H2 Zn finger	246..266	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..297	CDD:275368	11/19 (58%)
znf362a	NP_001071201.1	C2H2 Zn finger	257..277	CDD:275368
		zf-H2C2_2	269..294	CDD:290200	8/14 (57%)
		C2H2 Zn finger	285..305	CDD:275368	12/19 (63%)
		zf-H2C2_2	297..322	CDD:290200	15/24 (63%)
		COG5048	309..>403	CDD:227381	53/94 (56%)
		C2H2 Zn finger	313..333	CDD:275368	12/19 (63%)
		zf-H2C2_2	325..352	CDD:290200	19/26 (73%)
		C2H2 Zn finger	341..363	CDD:275368	15/21 (71%)
		zf-H2C2_2	355..379	CDD:290200	14/23 (61%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	401..421	CDD:275368	11/19 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I12363
eggNOG	1	0.900	-	-		E33208_3BF42
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25947
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.900