back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sqz and ZNF79

DIOPT Version :10

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_009066.2	Gene:	ZNF79 / 7633	HGNCID:	13153	Length:	498	Species:	Homo sapiens

Alignment Length:	295	Identity:	94/295 - (31%)
Similarity:	136/295 - (46%)	Gaps:	49/295 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 HDYKPFNISEFRQNVAERLDYSLKNGLVQHQQQMVMEQQPHPDQQ------------QQQHLHHP 89
            |..||:..:|..:      .:|..:.|.|||:....| :|:...:            |.|.:|..
Human   188 HRAKPYACNECGK------AFSYCSSLSQHQKSHTGE-KPYECSECGKAFSQSSSLIQHQRIHTG 245

  Fly    90 QQQQHPPQLKVSYSAPNSPPTPHEQQEQKYDPNR-SPPRQQMSSASGSGSN-----GSSPEE--- 145
            ::.....:...::| .|:..|.|::......|.| |...:..|..|....:     |..|.|
Human   246 EKPYKCSECGRAFS-QNANLTKHQRTHTGEKPYRCSECEKAFSDCSALVQHQRIHTGEKPYECSD 309

  Fly   146 -------------ESRRGDGDQAKPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQ 197
                         ..|...|:  |||||..|.|:|:..:...||.|||.|.|||||..|.:.|:|
Human   310 CGKAFRHSANLTNHQRTHTGE--KPYKCSECGKAFSYCAAFIQHQRIHTGEKPYRCAACGKAFSQ 372

  Fly   198 LSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEH 262
            .::|..|.|||||:|||||  :.|.|||||.:||..|.:.|..:||:|||.|.|.||:...|:.|
Human   373 SANLTNHQRTHTGEKPYKC--SECGKAFSQSTNLIIHQKTHTGEKPYKCNECGKFFSESSALIRH 435

  Fly   263 IPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKH 297
            ...|...   |.:.||.|||::.|.:.|.:|.:.|
Human   436 HIIHTGE---KPYECNECGKAFNQSSSLSQHQRIH 467

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.