Protein Alignment sqz and ZNF22

DIOPT Version :10

• Sequence 1: NP_524403.1
• Gene: sqz / 42300
• FlyBaseID: FBgn0010768
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_008894.2
• Gene: ZNF22 / 7570
• HGNCID: 13012
• Length: 224
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 80/223 - (35%)
• Similarity: 119/223 - (53%)
• Gaps: 14/223 - (6%)

  Fly   105 PNSPPTPHEQQEQKYDPNRSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAKPYKCGSCSKSFAN 169
            |.:..:....|.:.|:..|...||:..  .|......|.....||...|  |||||..|.|||:.
Human     6 PKAGISRSSSQGKAYENKRKTGRQRQK--WGMTIRFDSSFSRLRRSLDD--KPYKCTECEKSFSQ 66

  Fly   170 SSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSH 234
            ||.|.||.:||.|.|.::|..|.:.|.|.|:|.||.|.|||:|||||..  |.::|.|.|||..|
Human    67 SSTLFQHQKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDE--CGESFKQSSNLIQH 129

  Fly   235 SRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAE 299
            .|.|..:||::|:.|.:|||....|::|...|...   |.:.|:.|||.::|.::|::|::.|.|
Human   130 QRIHTGEKPYQCDECGRCFSQSSHLIQHQRTHTGE---KPYQCSECGKCFSQSSHLRQHMKVHKE 191

  Fly   300 KAEKQQHRHTAQVAAHQQHVPA--SGIG 325
            :..::......:|   :.|:|:  :|.|
Human   192 EKPRKTRGKNIRV---KTHLPSWKAGTG 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	10/19 (53%)
		COG5048	184..>288	CDD:227381	43/103 (42%)
		C2H2 Zn finger	188..208	CDD:275368	9/19 (47%)
		C2H2 Zn finger	216..238	CDD:275368	9/21 (43%)
		C2H2 Zn finger	246..266	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..297	CDD:275368	7/19 (37%)
ZNF22	NP_008894.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		6/29 (21%)
		COG5048	<41..194	CDD:227381	68/159 (43%)
		C2H2 Zn finger	57..77	CDD:275368	10/19 (53%)
		C2H2 Zn finger	85..105	CDD:275368	9/19 (47%)
		C2H2 Zn finger	113..133	CDD:275368	9/21 (43%)
		C2H2 Zn finger	141..161	CDD:275368	7/19 (37%)
		C2H2 Zn finger	169..189	CDD:275368	7/19 (37%)