Protein Alignment sqz and ZNF692

DIOPT Version :10

• Sequence 1: NP_524403.1
• Gene: sqz / 42300
• FlyBaseID: FBgn0010768
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001129508.1
• Gene: ZNF692 / 55657
• HGNCID: 26049
• Length: 524
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 59/238 - (24%)
• Similarity: 96/238 - (40%)
• Gaps: 29/238 - (12%)

  Fly    96 PQLKVSYSAPNSPPTPHEQQEQKYDPNRSPPRQQMSSASGSGSNGSSP-----EEES-------- 147
            |.|..|..:..:|| |.|.:.|..........||..:.:.:||...|.     :|::
Human   261 PALSASSLSSRAPP-PAEVRVQPQLSRTPQAAQQTEALASTGSQAQSAPTPAWDEDTAQIGPKRI 324

  Fly   148 RRGDGDQAKPYKCGSCSKSFANSSYLSQHTRI-HLGIKPYRC--EICQRKFTQLSHLQQHIRTHT 209
            |:....:..|.....|.:.|:|..||:.|.:. |:..|.:.|  ..|.:.|....||::|::.|:
Human   325 RKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFSCPEPACGKSFNFKKHLKEHMKLHS 389

  Fly   210 GDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKT 274
            ..:.|.|..  |.::|...|||..|.|.|..:||.:|..|......:.:|..|..||.::.....
Human   390 DTRDYICEF--CARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHQRKHAETVAALR 452

  Fly   275 HICNLCGKSYTQETYLQKHLQKHAEKAEKQQHRHTAQVAAHQQ 317
            ..|..|||.:.:...:..|..|          .|.|.:.|.|:
Human   453 FPCEFCGKRFEKPDSVAAHRSK----------SHPALLLAPQE 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	6/20 (30%)
		COG5048	184..>288	CDD:227381	30/105 (29%)
		C2H2 Zn finger	188..208	CDD:275368	6/21 (29%)
		C2H2 Zn finger	216..238	CDD:275368	8/21 (38%)
		C2H2 Zn finger	246..266	CDD:275368	4/19 (21%)
		C2H2 Zn finger	277..297	CDD:275368	5/19 (26%)
ZNF692	NP_001129508.1	kgd	213..>330	CDD:476867	15/69 (22%)
		SFP1	<295..413	CDD:227516	28/119 (24%)
		COG5236	<363..>490	CDD:227561	35/135 (26%)
		C2H2 Zn finger	366..388	CDD:275368	6/21 (29%)
		C2H2 Zn finger	396..416	CDD:275368	8/21 (38%)
		C2H2 Zn finger	424..444	CDD:275368	4/19 (21%)
		C2H2 Zn finger	455..472	CDD:275368	4/16 (25%)