DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sqz and esg

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	82/316 - (25%)
Similarity:	132/316 - (41%)	Gaps:	61/316 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PTAPN------GVPSGDYLHRSIDQLRSLGHLTTAQLVHDYKPFNISEFRQNVAERLDYSLKNGL 63
            |::|:      ..|...|||   .:..|:.....::::|  :|.                   |:
  Fly   163 PSSPSDSLGSLSPPPHHYLH---GRASSVSPPMRSEIIH--RPI-------------------GV 203

  Fly    64 VQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHP--------------PQLKVSYSAPNSPPTPHEQ 114
            .||:.....:...:|......|.||......|              |:...|.|.|......|
  Fly   204 RQHRFLPYPQMPGYPSLGGYTHTHHHHAPISPAYSENSYYSMRSMTPESSCSSSLPEDLSLKH-- 266

  Fly   115 QEQKYDPNRSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAKPYKCGSCSKSFANSSYLSQHTRI 179
            :....:.|.|.|.:|.::.:|..|..:.|...::: |.:|...|:|..|.||::..|.|::|.:.
  Fly   267 KNLNLNLNTSQPGEQAAAKTGDMSPETMPNASAKK-DKNQPPRYQCPDCQKSYSTFSGLTKHQQF 330

  Fly   180 HLGI-------KPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRC 237
            |...       |.:.|:.|.:.:..|..|:.||||||  .|.||..  |.||||:...||.|.|.
  Fly   331 HCPAAEGNQVKKSFSCKDCDKTYVSLGALKMHIRTHT--LPCKCNL--CGKAFSRPWLLQGHIRT 391

  Fly   238 HQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKH 293
            |..:|||.|..|::.|:|...|..|:..|.|   :|.:.|..|.|::::.:.|.||
  Fly   392 HTGEKPFSCQHCHRAFADRSNLRAHLQTHSD---IKKYSCTSCSKTFSRMSLLTKH 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	7/19 (37%)
		zf-H2C2_2	172..197	CDD:290200	6/31 (19%)
		zf-C2H2	186..208	CDD:278523	7/21 (33%)
		C2H2 Zn finger	188..208	CDD:275368	7/19 (37%)
		zf-C2H2_8	191..271	CDD:292531	33/79 (42%)
		zf-H2C2_2	200..227	CDD:290200	14/26 (54%)
		C2H2 Zn finger	216..238	CDD:275368	10/21 (48%)
		C2H2 Zn finger	246..266	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	6/17 (35%)
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	8/21 (38%)
		C2H2 Zn finger	311..331	CDD:275370	7/19 (37%)
		zf-C2H2	344..366	CDD:278523	7/21 (33%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		zf-C2H2	370..392	CDD:278523	11/23 (48%)
		C2H2 Zn finger	372..392	CDD:275368	10/21 (48%)
		zf-H2C2_2	385..408	CDD:290200	10/22 (45%)
		zf-C2H2	398..420	CDD:278523	7/21 (33%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	428..444	CDD:275368	4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457134
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930