DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and CG42726

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	344	Identity:	90/344 - (26%)
Similarity:	147/344 - (42%)	Gaps:	55/344 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 DQAKPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCR 217
            |..|.:.|..|.:.||.||:|..|...|.....:.|.:|.:.|.|...||:|:.||..:| :.|
  Fly    96 DLLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEK-HLC- 158

  Fly   218 HAGCPKAFSQLSNLQSHSRCH-QTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCG 281
             ..|.|.|.:.|:|.||...| .....|||..|.|.|.::..|.:|:.|| |..::: |:|.:|.
  Fly   159 -PICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKH-DKNNIR-HMCKVCQ 220

  Fly   282 KSYTQETYLQKHLQKHAEKAEKQ-------QHRHTAQVAAH-QQHVPAS-------GIGLNLQRQ 331
            ||:.::|.|:.|:::|:.: |:|       .:.....:..| :||..|.       .|.:|.:..
  Fly   221 KSFLRQTTLRLHMKRHSNR-ERQSCSLCGKSYNDPDALGRHLRQHKTAERYRCIQCDITINRKDN 284

  Fly   332 AMNDVNAAYWAKMGADSAAASLAEAI-----QQQLPQAGGQPYG--NFASLQQQHQQQQQELLHH 389
            .:..:.:     |....|.||..|.:     .|:...|..:|..  .:.|:.|.....:..:|
  Fly   285 MLRHLRS-----MHPGCAFASTVEMVTPRSSAQEATTAEERPSQTVRYNSVIQSVGNVEPVML-- 342

  Fly   390 QRLADTPGHSHSPH-----EEAAGEDLVLRQSTPQHHLQ-----------QQQQQQQQQQAQQQQ 438
              |..||..|..|.     .:|..|.|.|....|:.::|           ::...:....||:..
  Fly   343 --LQSTPLPSQLPELQMEKGKAVPEHLPLPDVMPEENVQLYRKIILDLDNEEYSSEPSPDAQEPA 405

  Fly   439 QAQHQPS-PGPGNSAFTPL 456
            ...|||. ||.|:|.|:.:
  Fly   406 MQHHQPRVPGQGSSKFSEM 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	8/19 (42%)
		zf-H2C2_2	172..197	CDD:290200	6/24 (25%)
		zf-C2H2	186..208	CDD:278523	7/21 (33%)
		C2H2 Zn finger	188..208	CDD:275368	7/19 (37%)
		zf-C2H2_8	191..271	CDD:292531	29/80 (36%)
		zf-H2C2_2	200..227	CDD:290200	10/26 (38%)
		C2H2 Zn finger	216..238	CDD:275368	8/21 (38%)
		C2H2 Zn finger	246..266	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	7/19 (37%)
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368
		C2H2 Zn finger	103..123	CDD:275368	8/19 (42%)
		COG5048	<112..288	CDD:227381	52/181 (29%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	33/108 (31%)
		C2H2 Zn finger	158..178	CDD:275368	8/21 (38%)
		C2H2 Zn finger	187..207	CDD:275368	6/19 (32%)
		C2H2 Zn finger	216..236	CDD:275368	7/19 (37%)
		C2H2 Zn finger	244..264	CDD:275368	1/19 (5%)
		C2H2 Zn finger	272..290	CDD:275368	2/17 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930