DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and CG2712

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_570028.1	Gene:	CG2712 / 31267	FlyBaseID:	FBgn0024975	Length:	501	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	100/352 - (28%)
Similarity:	145/352 - (41%)	Gaps:	82/352 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QLVHDYKPFNISEFRQNVAERLDYSLKNGLV--------QHQQQMVMEQQPHPDQQQQQHLHHPQ 90
            ::|.|..|    |.|::..||.:.:|:..:.        ..|..|.:..||...|:...|.....
  Fly   178 EIVDDPDP----EQRRSRLERSEPALQCPICGKQLARKRTFQYHMRLHGQPKIRQEDNDHCIEEC 238

  Fly    91 QQQHPP-QLK--------VSYSAPNSPPTPHEQQEQKYDPNRSPP-------------RQQMSSA 133
            .|..|. |.|        |..||..|       ..||..|:.|.|             .:|:|:.
  Fly   239 LQVEPVLQAKAGEDVYEIVEKSAQTS-------ATQKTLPSGSRPWKPLNPSLQCKICGKQLSTN 296

  Fly   134 S---------GSGSN------GSSPEEESRRGDG-----DQAKPYKCGSCSKSFANSSYLSQHTR 178
            :         |:.:.      |.|.:..:.| ||     |:..|.:|.:|.|.:..:|.|..|..
  Fly   297 NSFKYHMQLHGTATPYVCTICGESFKTRNAR-DGHVTLHDRNNPNRCPTCFKVYRQASSLRTHLL 360

  Fly   179 IHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKP 243
            ||.||||:.|.||.::.||.|..::|:.||||:||:.|..  |.:.|...|||.:|.|||..:||
  Fly   361 IHSGIKPFECSICGKRLTQKSGYKKHMLTHTGEKPHGCDI--CGRRFRYSSNLIAHKRCHSQEKP 423

  Fly   244 FKCNSCYK-CFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEKAEKQQHR 307
            ..|..|.| .|.....|..|:..|...:...   |..||||:.:...|..|.|.|  ||.:|:.|
  Fly   424 HPCPVCQKRSFGSTSELNRHMLVHSSERPFG---CEQCGKSFKRRISLAIHRQSH--KAGRQRRR 483

  Fly   308 HTAQVAAHQQHVPASGIGLNLQRQAMN 334
                 |.|:       :|:.|:.|..|
  Fly   484 -----AEHE-------VGVQLEEQDEN 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	6/19 (32%)
		zf-H2C2_2	172..197	CDD:290200	11/24 (46%)
		zf-C2H2	186..208	CDD:278523	7/21 (33%)
		C2H2 Zn finger	188..208	CDD:275368	7/19 (37%)
		zf-C2H2_8	191..271	CDD:292531	30/80 (38%)
		zf-H2C2_2	200..227	CDD:290200	10/26 (38%)
		C2H2 Zn finger	216..238	CDD:275368	8/21 (38%)
		C2H2 Zn finger	246..266	CDD:275368	6/20 (30%)
		C2H2 Zn finger	277..297	CDD:275368	8/19 (42%)
CG2712	NP_570028.1	zf-AD	13..92	CDD:214871
		C2H2 Zn finger	286..306	CDD:275368	2/19 (11%)
		C2H2 Zn finger	314..334	CDD:275368	5/20 (25%)
		C2H2 Zn finger	342..362	CDD:275368	6/19 (32%)
		zf-H2C2_2	354..379	CDD:290200	11/24 (46%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		COG5048	378..>463	CDD:227381	34/89 (38%)
		zf-H2C2_2	384..407	CDD:290200	10/24 (42%)
		C2H2 Zn finger	398..418	CDD:275368	8/21 (38%)
		C2H2 Zn finger	426..447	CDD:275368	6/20 (30%)
		zf-H2C2_2	439..464	CDD:290200	8/27 (30%)
		C2H2 Zn finger	455..475	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100