DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and Zfp362

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001178541.1	Gene:	Zfp362 / 297879	RGDID:	1306498	Length:	418	Species:	Rattus norvegicus

Alignment Length:	343	Identity:	119/343 - (34%)
Similarity:	155/343 - (45%)	Gaps:	102/343 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 QQQMVMEQQPHPDQQQQQHLHHPQQQQ----HP----------------------------PQLK 99
            ||.:::  .|.|.:..|..:..|:.||    ||                            |.:.
  Rat    66 QQPLLV--PPAPAESSQAVMSLPKLQQVPGLHPQSVPQPDVALHARPATSTVTGLGLSSRTPAVS 128

  Fly   100 VSYSAP------NSPPTPHEQQEQKY---DPN-----RSPP-RQQMSSASGSGSNGSSPEEESRR 149
            .|.|.|      ::|.||....:.:.   .|.     .||| ...:.:..|.|..|....|..|:
  Rat   129 TSESTPGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRK 193

  Fly   150 --------------------GDGD-------------------------------QAKPYKCGSC 163
                                ..|:                               :|||:||..|
  Rat   194 KIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHC 258

  Fly   164 SKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQL 228
            ||||||:|||:||.|||||:|||.|..|.:.|.||||||||.|.||||:||||.|.||.|||:||
  Rat   259 SKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQL 323

  Fly   229 SNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKH 293
            ||||||.|.|..|||:||.:||:.:||..:|..|:..|. .||.|.:.|::||::||.||||.||
  Rat   324 SNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHA-IKHAKAYCCSMCGRAYTSETYLMKH 387

  Fly   294 LQKHAEKAEKQQHRHTAQ 311
            :.||........| |:.|
  Rat   388 MSKHTVVEHLVSH-HSPQ 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	14/19 (74%)
		zf-H2C2_2	172..197	CDD:290200	15/24 (63%)
		zf-C2H2	186..208	CDD:278523	13/21 (62%)
		C2H2 Zn finger	188..208	CDD:275368	12/19 (63%)
		zf-C2H2_8	191..271	CDD:292531	47/79 (59%)
		zf-H2C2_2	200..227	CDD:290200	20/26 (77%)
		C2H2 Zn finger	216..238	CDD:275368	16/21 (76%)
		C2H2 Zn finger	246..266	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..297	CDD:275368	11/19 (58%)
Zfp362	NP_001178541.1	PRK14971	<27..>131	CDD:237874	11/66 (17%)
		C2H2 Zn finger	227..247	CDD:275368	0/19 (0%)
		zf-H2C2_2	239..264	CDD:404364	10/24 (42%)
		zf-C2H2	253..275	CDD:395048	15/21 (71%)
		C2H2 Zn finger	255..275	CDD:275368	14/19 (74%)
		zf-H2C2_2	267..292	CDD:404364	15/24 (63%)
		C2H2 Zn finger	283..303	CDD:275368	12/19 (63%)
		SFP1	<305..357	CDD:227516	32/51 (63%)
		C2H2 Zn finger	311..333	CDD:275368	16/21 (76%)
		C2H2 Zn finger	341..361	CDD:275368	7/19 (37%)
		C2H2 Zn finger	373..391	CDD:275368	10/17 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BF42
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810