DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and Zfp384

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001359349.1	Gene:	Zfp384 / 269800	MGIID:	2443203	Length:	615	Species:	Mus musculus

Alignment Length:	321	Identity:	128/321 - (39%)
Similarity:	157/321 - (48%)	Gaps:	102/321 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 KPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAG 220
            ||:||..|||:|||:|||:||.|||.|.|||.|..||:.|.||||||||.|.||||:||||.|.|
Mouse   347 KPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPG 411

  Fly   221 CPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYT 285
            |.|||:||||||||.|.|..||||||::|::.::|..:|..|:..| ..||.|.:.|.:|.::||
Mouse   412 CEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTH-TVKHAKVYTCTICSRAYT 475

  Fly   286 QETYLQKHLQKHAEKAEKQQHRHTAQVAAHQQHVPASGIGLNLQRQAMNDVNAAYWAKMGADSAA 350
            .||||.||::||                    :.|      :||:|    |.||        :||
Mouse   476 SETYLMKHMRKH--------------------NPP------DLQQQ----VQAA--------AAA 502

  Fly   351 ASLAEAIQQQLPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSHSPHEEAAGEDLVLRQ 415
            |::|:|..|...||..|     |..|.|.|.|.|
Mouse   503 AAVAQAQAQAQAQAQAQ-----AQAQAQAQAQAQ------------------------------- 531

  Fly   416 STPQHHLQQQQQQQQQQQAQQQQQAQHQPSPGPGNSAFTPLSATVAPPPHLQQHRGPPGSA 476
                   .|.|.|.|..||.|||| |.||.|               .|||.|.    ||:|
Mouse   532 -------AQAQAQAQASQASQQQQ-QQQPPP---------------QPPHFQS----PGAA 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	13/19 (68%)
		zf-H2C2_2	172..197	CDD:290200	15/24 (63%)
		zf-C2H2	186..208	CDD:278523	14/21 (67%)
		C2H2 Zn finger	188..208	CDD:275368	13/19 (68%)
		zf-C2H2_8	191..271	CDD:292531	47/79 (59%)
		zf-H2C2_2	200..227	CDD:290200	20/26 (77%)
		C2H2 Zn finger	216..238	CDD:275368	16/21 (76%)
		C2H2 Zn finger	246..266	CDD:275368	5/19 (26%)
		C2H2 Zn finger	277..297	CDD:275368	10/19 (53%)
Zfp384	NP_001359349.1	C2H2 Zn finger	262..282	CDD:275368
		COG5048	<285..440	CDD:227381	65/92 (71%)
		C2H2 Zn finger	290..310	CDD:275368
		C2H2 Zn finger	318..338	CDD:275368
		C2H2 Zn finger	351..371	CDD:275368	13/19 (68%)
		C2H2 Zn finger	379..399	CDD:275368	13/19 (68%)
		C2H2 Zn finger	407..429	CDD:275368	16/21 (76%)
		C2H2 Zn finger	437..457	CDD:275368	5/19 (26%)
		C2H2 Zn finger	467..487	CDD:275368	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7661
SonicParanoid	1	1.000	-	-		X6293
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940