DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and Zfp367

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_780703.1	Gene:	Zfp367 / 238673	MGIID:	2442266	Length:	340	Species:	Mus musculus

Alignment Length:	330	Identity:	76/330 - (23%)
Similarity:	114/330 - (34%)	Gaps:	119/330 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 RSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAK-------PYKCGSCSKSFANSSYLSQHTRIH 180
            |..|:   ||||.:..:|...|||:...|....|       |.  ....:...|.   .:|:...
Mouse   100 RGAPQ---SSASVAAVSGGEDEEEASSPDSGHLKDGIRRGRPR--ADTVRDLINE---GEHSSSR 156

  Fly   181 LGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFK 245
            :     ||.||.|.|.:...||.|.|||||::||.|.:..|.|||.|...|::|.|.|..:|||.
Mouse   157 I-----RCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFV 216

  Fly   246 C--NSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEKAEKQQHRH 308
            |  |.|...|                                  |:..:|..|| ..|..::...
Mouse   217 CSENGCLSRF----------------------------------THANRHCPKH-PYARLKREEP 246

  Fly   309 TAQVAAHQQHVPASGIGLNLQRQAMNDVNAAYWAKMGADSAAASLAEAIQQQLPQAGGQPYGNFA 373
            |..::.||          :...:|..:..|.||             |..:|:.|...|:
Mouse   247 TDALSKHQ----------SPDNKAAAEWLAKYW-------------EMREQRTPTLKGK------ 282

  Fly   374 SLQQQHQQQQQELLHHQRLADTPGHSHSPHEEAAGEDLVLRQSTPQHHLQQQQQQQQQQQAQQQQ 438
             |.|:..|:||:                                |..:||..::..::..||::.
Mouse   283 -LVQKADQEQQD--------------------------------PLEYLQSDEEDDEKSGAQRRL 314

  Fly   439 QAQHQ 443
            |.|.:
Mouse   315 QEQRE 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	2/19 (11%)
		zf-H2C2_2	172..197	CDD:290200	7/24 (29%)
		zf-C2H2	186..208	CDD:278523	10/21 (48%)
		C2H2 Zn finger	188..208	CDD:275368	9/19 (47%)
		zf-C2H2_8	191..271	CDD:292531	30/81 (37%)
		zf-H2C2_2	200..227	CDD:290200	15/26 (58%)
		C2H2 Zn finger	216..238	CDD:275368	9/21 (43%)
		C2H2 Zn finger	246..266	CDD:275368	4/21 (19%)
		C2H2 Zn finger	277..297	CDD:275368	2/19 (11%)
Zfp367	NP_780703.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..140		12/43 (28%)
		COG5048	157..>230	CDD:227381	34/111 (31%)
		zf-C2H2	158..179	CDD:278523	10/20 (50%)
		C2H2 Zn finger	159..179	CDD:275368	9/19 (47%)
		zf-H2C2_2	171..198	CDD:290200	15/26 (58%)
		C2H2 Zn finger	187..209	CDD:275368	9/21 (43%)
		zf-H2C2_2	202..228	CDD:290200	11/59 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..317		12/75 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960