DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqz and Zfp384

DIOPT Version :9

Sequence 1:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	XP_038962888.1	Gene:	Zfp384 / 171018	RGDID:	708346	Length:	680	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	123/321 - (38%)
Similarity:	150/321 - (46%)	Gaps:	105/321 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 KPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAG 220
            ||:||..|||:|||:|||:||.|||.|.|||.|..||:.|.||||||||.|.||||:||||.|.|
  Rat   415 KPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPG 479

  Fly   221 CPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYT 285
            |.|||:||||||||.|.|..||||||::|::.::|..:|..|:..| ..||.|.:.|.:|.::||
  Rat   480 CEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTH-TVKHAKVYTCTICSRAYT 543

  Fly   286 QETYLQKHLQKHAEKAEKQQHRHTAQVAAHQQHVPASGIGLNLQRQAMNDVNAAYWAKMGADSAA 350
            .||||.||::||                    :.|      :||:|..                |
  Rat   544 SETYLMKHMRKH--------------------NPP------DLQQQVQ----------------A 566

  Fly   351 ASLAEAIQQQLPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSHSPHEEAAGEDLVLRQ 415
            |:.|.|:.|...||..|     |..|.|.|.|.|
  Rat   567 AAAAAAVAQAQAQAQAQ-----AQAQAQAQAQAQ------------------------------- 595

  Fly   416 STPQHHLQQQQQQQQQQQAQQQQQAQHQPSPGPGNSAFTPLSATVAPPPHLQQHRGPPGSA 476
                   .|.|.|.|..||.||||.|..|.|               .|||.|.    ||:|
  Rat   596 -------AQAQAQAQASQASQQQQQQQPPPP---------------QPPHFQS----PGAA 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	13/19 (68%)
		zf-H2C2_2	172..197	CDD:290200	15/24 (63%)
		zf-C2H2	186..208	CDD:278523	14/21 (67%)
		C2H2 Zn finger	188..208	CDD:275368	13/19 (68%)
		zf-C2H2_8	191..271	CDD:292531	47/79 (59%)
		zf-H2C2_2	200..227	CDD:290200	20/26 (77%)
		C2H2 Zn finger	216..238	CDD:275368	16/21 (76%)
		C2H2 Zn finger	246..266	CDD:275368	5/19 (26%)
		C2H2 Zn finger	277..297	CDD:275368	10/19 (53%)
Zfp384	XP_038962888.1	C2H2 Zn finger	330..350	CDD:275368
		COG5048	<353..508	CDD:227381	65/92 (71%)
		C2H2 Zn finger	358..378	CDD:275368
		C2H2 Zn finger	386..406	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368	13/19 (68%)
		C2H2 Zn finger	447..467	CDD:275368	13/19 (68%)
		C2H2 Zn finger	475..497	CDD:275368	16/21 (76%)
		C2H2 Zn finger	505..525	CDD:275368	5/19 (26%)
		C2H2 Zn finger	535..555	CDD:275368	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6293
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000