DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11779 and TIM44-1

DIOPT Version :9

Sequence 1:	NP_650786.2	Gene:	CG11779 / 42298	FlyBaseID:	FBgn0038683	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001325326.1	Gene:	TIM44-1 / 816572	AraportID:	AT2G20510	Length:	509	Species:	Arabidopsis thaliana

Alignment Length:	496	Identity:	116/496 - (23%)
Similarity:	204/496 - (41%)	Gaps:	95/496 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IAALVRDRACLFTCQQASQNLQQQ-------QPRFYSAPG----RRAGFFSQFFDNMKAEMDKNK 88
            |..::||  .|.|.|...:.|..|       :..|..|.|    ||...|::|..|::.|...|.
plant    38 IRKIIRD--LLITKQPLLRQLFHQRVLRANARSEFLPAIGYTSHRRFSVFTEFSKNIRGEAHSNP 100

  Fly    89 EIKDNIRKFREEAQKL------------EESDAL-KSARQKFNIVESEAQKSSSMLKEQLGAIKE 140
            |.:..:::.:|..::.            :.::.| |.|...:...||.|:|.||.:|::|.|..|
plant   101 EFERTVKELKERTEEFKGVTEDLKVRTKQTTEKLYKQADGVWTEAESAAKKVSSSVKDKLSAASE 165

  Fly   141 RVGDVLEDASKSHLAKKVTEELSKKARGVSDTISDT---SGKLGQTSAFQAISNTTTTIKKEMDS 202
            .|              |.:.:|.|:....|.:.|.|   .|:..|:.:.:.:.......|..:.|
plant   166 EV--------------KESFKLGKEENAESASSSGTRASQGEKQQSGSTEELHTFFAKFKSSLSS 216

  Fly   203 ASIENRVYR----APAKLRKRVQLVMSDS-------DRVVE-----PNTEATGMELH------KD 245
            ..:....||    .|..:.|:...::.|.       .:.:|     |.|....|...      |.
plant   217 PKVSEVFYRLKEAKPFDIVKQALDIVKDELRGNPSRKKFLEHTPPPPFTGERSMRTEMVVTQTKQ 281

  Fly   246 SKFYESWENFKN--------------NNTYVNK----VLDWKVKYDESENPVIRASRLLTDKVSD 292
            ||..:.||:|:.              :...|||    ..|.:..::.|:||::.       |:.|
plant   282 SKLQQKWESFREKMQGSPVFKRLSGMSEPVVNKSQEIAEDVREIWETSDNPIVH-------KIQD 339

  Fly   293 VMGGLFSKTELSETMTELVKIDPSFDQKDFLRDCETDIIPNILESIVRGDLEILKDWCFESTFNI 357
            :......:|:.:.|..|:...||||...||..:.| ::|..:|.:...||:|.||.:|.:.....
plant   340 MNEKFLKETDSASTYKEIRSRDPSFSLPDFAAEIE-EVIKPVLNAYSEGDVETLKKYCSKEVIER 403

  Fly   358 IANPIKEAKKAGVYLDSKILDIENIELAMGKVMEQGPVLIITFQAQQIMCVRDQKSQVVEGDPEK 422
            ........:..||..|:|:|.|..:.:::.|:|...|::|..||.|:|.||||:..::.||..:.
plant   404 CTAERTAYQTHGVLFDNKLLHISEVSVSVTKMMGDSPIIIAKFQTQEIYCVRDENGEIQEGGQDT 468

  Fly   423 VMRVHYVWVLCR-DRNELNPKA---AWRLMELSANSSEQFV 459
            :..|::.|.:.: :..||...|   .|||.|:..|..:..:
plant   469 IHTVYHEWAMQQVETTELGEDAIYPIWRLREMCRNGVQALI 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11779	NP_650786.2	3a0801s03tim44	78..449	CDD:130057	99/430 (23%)
CG11779	NP_650786.2	Tim44	304..452	CDD:282178	46/151 (30%)
TIM44-1	NP_001325326.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	84	1.000	Domainoid score	I2849
eggNOG	1	0.900	-	-		E1_KOG2580
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I1958
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1041560at2759
OrthoFinder	1	1.000	-	-		FOG0003783
OrthoInspector	1	1.000	-	-		otm2714
orthoMCL	1	0.900	-	-		OOG6_102237
Panther	1	1.100	-	-	O	PTHR10721
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3720
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830