DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11779 and Timm44

DIOPT Version :9

Sequence 1:	NP_650786.2	Gene:	CG11779 / 42298	FlyBaseID:	FBgn0038683	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_058963.2	Gene:	Timm44 / 29635	RGDID:	3864	Length:	453	Species:	Rattus norvegicus

Alignment Length:	440	Identity:	216/440 - (49%)
Similarity:	319/440 - (72%)	Gaps:	23/440 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 RACLFTCQQ--ASQNL-------QQQQP-------RFYSAPGRRAGFFSQFFDNMKAEMDKNKEI 90
            |.||.:..|  :|.||       |..:|       :.||: |.|.||.|...||:|.|:.||||:
  Rat    15 RRCLGSGIQFLSSHNLPRGGSSYQISRPGGELTLTKSYSS-GSRKGFLSGLLDNIKQELAKNKEM 78

  Fly    91 KDNIRKFREEAQKLEESDALKSARQKFNIVESEAQKSSSMLKEQLGAIKERVGDVLEDASKSHLA 155
            |::|:|||:||:||||||||:.||:|:..:|||..::|..:|::||.:...|.:.|::.|||.|.
  Rat    79 KESIKKFRDEAKKLEESDALQEARRKYKTIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLG 143

  Fly   156 KKV---TEELSKKARGVSDTISDTSGKLGQTSAFQAISNTTTTIKKEMDSASI-ENRVYRAPAKL 216
            :|:   .||.::.|:..::::|....|||:|:||:|||....::|||:|.:.: ....||.|.:|
  Rat   144 RKIKEGVEEAARTAKQSAESVSKGGEKLGKTAAFKAISQGVESVKKEIDESVLGHTGTYRRPERL 208

  Fly   217 RKRVQLVMS--DSDRVVEPNTEATGMELHKDSKFYESWENFKNNNTYVNKVLDWKVKYDESENPV 279
            |||.:...:  ...:|.|.|.||.|:.||||||:|:.|::||:||...|:..:.|:|||||:|.:
  Rat   209 RKRTEFAGAKFKESKVFEANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMKMKYDESDNVL 273

  Fly   280 IRASRLLTDKVSDVMGGLFSKTELSETMTELVKIDPSFDQKDFLRDCETDIIPNILESIVRGDLE 344
            |||||.|||||:|::||||||||:||.:||::::||:||:..||..|||||||||||:::.|:|:
  Rat   274 IRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDRFLHQCETDIIPNILEAMISGELD 338

  Fly   345 ILKDWCFESTFNIIANPIKEAKKAGVYLDSKILDIENIELAMGKVMEQGPVLIITFQAQQIMCVR 409
            ||||||:|:|:|.:|:.|::||..|:...|:||||.|::|||||:||||||||:|||||.:|.::
  Rat   339 ILKDWCYEATYNQLAHSIQQAKALGLQFHSRILDISNVDLAMGKMMEQGPVLIVTFQAQLVMVIK 403

  Fly   410 DQKSQVVEGDPEKVMRVHYVWVLCRDRNELNPKAAWRLMELSANSSEQFV 459
            :.|.:|.:|||:||:|:.|||.||||:.||||.|||||:::||:|:||.:
  Rat   404 NPKGEVFDGDPDKVLRMLYVWALCRDQEELNPYAAWRLLDISASSTEQIL 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11779	NP_650786.2	3a0801s03tim44	78..449	CDD:130057	195/376 (52%)
CG11779	NP_650786.2	Tim44	304..452	CDD:282178	86/147 (59%)
Timm44	NP_058963.2	3a0801s03tim44	66..443	CDD:130057	195/376 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341537
Domainoid	1	1.000	223	1.000	Domainoid score	I2491
eggNOG	1	0.900	-	-		E1_KOG2580
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4631
Inparanoid	1	1.050	428	1.000	Inparanoid score	I1674
OMA	1	1.010	-	-		QHG52906
OrthoDB	1	1.010	-	-		D1041560at2759
OrthoFinder	1	1.000	-	-		FOG0003783
OrthoInspector	1	1.000	-	-		oto97334
orthoMCL	1	0.900	-	-		OOG6_102237
Panther	1	1.100	-	-	LDO	PTHR10721
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3720
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770