DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11779 and timm44

DIOPT Version :9

Sequence 1:	NP_650786.2	Gene:	CG11779 / 42298	FlyBaseID:	FBgn0038683	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	XP_012811621.2	Gene:	timm44 / 100145471	XenbaseID:	XB-GENE-946996	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	431	Identity:	219/431 - (50%)
Similarity:	321/431 - (74%)	Gaps:	14/431 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ALVRDRA--CLFTCQQASQNLQQQQPRFYSAPGRRAGFFSQFFDNMKAEMDKNKEIKDNIRKFRE 99
            :||:||:  |:     ....|..||.|:||:.||| ||.....||:|.|:.||||:|:||:||||
Frog    27 SLVKDRSVYCV-----GCPTLVCQQMRYYSSSGRR-GFLGGLLDNIKQELSKNKEMKENIKKFRE 85

  Fly   100 EAQKLEESDALKSARQKFNIVESEAQKSSSMLKEQLGAIKERVGDVLEDASKSHLAKKV---TEE 161
            ||:||||||||:.||:||..:|.|..|:|.:.|::...:.:.|.:.|::..|:.|.:|.   .||
Frog    86 EAKKLEESDALQQARRKFKTIELETMKTSEVFKKKFEQMSDTVKESLDEVGKTDLGRKFRESVEE 150

  Fly   162 LSKKARGVSDTISDTSGKLGQTSAFQAISNTTTTIKKEMDSASI-ENRVYRAPAKLRKRVQLV-- 223
            .:|.|:..:::::....|:|:|:||:|||....|:|||.|.:.: :...||.|::||||.:..
Frog   151 AAKTAKQSAESVTKGGEKIGKTAAFKAISQGVETVKKEFDESVLGQTGPYRPPSRLRKRSEFSGD 215

  Fly   224 MSDSDRVVEPNTEATGMELHKDSKFYESWENFKNNNTYVNKVLDWKVKYDESENPVIRASRLLTD 288
            .:..:::.|.|.||.||.||||||:|:.|::||:||...|:..:.|:|||||:|..:||||.:||
Frog   216 RTKEEKIFEANEEAMGMVLHKDSKWYQQWKDFKDNNMVFNRFFEMKMKYDESDNAFVRASRTITD 280

  Fly   289 KVSDVMGGLFSKTELSETMTELVKIDPSFDQKDFLRDCETDIIPNILESIVRGDLEILKDWCFES 353
            ||||::||||||||:||.:||::|:||:||:..||:.||.||||||||:::||||::|||||:|:
Frog   281 KVSDLIGGLFSKTEMSEVLTEILKVDPNFDKDKFLKLCERDIIPNILEAMIRGDLDVLKDWCYEA 345

  Fly   354 TFNIIANPIKEAKKAGVYLDSKILDIENIELAMGKVMEQGPVLIITFQAQQIMCVRDQKSQVVEG 418
            |::.:|:||::||..|:..:||||||:||:|||||:||||||||||||||.:|.:.:||..||||
Frog   346 TYSQLAHPIQQAKAMGLQFNSKILDIDNIDLAMGKMMEQGPVLIITFQAQLVMVITNQKGDVVEG 410

  Fly   419 DPEKVMRVHYVWVLCRDRNELNPKAAWRLMELSANSSEQFV 459
            |.:||:|:.|||.||||::||||.|||||:::|:::|||.:
Frog   411 DRDKVLRMLYVWALCRDQDELNPYAAWRLLDISSSASEQIL 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11779	NP_650786.2	3a0801s03tim44	78..449	CDD:130057	199/376 (53%)
CG11779	NP_650786.2	Tim44	304..452	CDD:282178	92/147 (63%)
timm44	XP_012811621.2	3a0801s03tim44	64..441	CDD:130057	199/376 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	231	1.000	Domainoid score	I2393
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4631
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1963
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1041560at2759
OrthoFinder	1	1.000	-	-		FOG0003783
OrthoInspector	1	1.000	-	-		oto104017
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3720
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060