DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppcs and ppcs

DIOPT Version :9

Sequence 1:	NP_650784.3	Gene:	Ppcs / 42295	FlyBaseID:	FBgn0261285	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001072632.1	Gene:	ppcs / 780088	XenbaseID:	XB-GENE-954648	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	291	Identity:	137/291 - (47%)
Similarity:	193/291 - (66%)	Gaps:	2/291 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LKEFCERHNKLQNRIVLVTSGGTTVPLEHNTVRFVDNFSAGTRGSASAEYFLDHDYAVIFMHRHK 88
            :.||...|.....|:||:|||||.||||..||||:||||:|.||||||||||...|||||:|||:
Frog     1 MAEFARDHGSRGTRVVLITSGGTKVPLESRTVRFLDNFSSGRRGSASAEYFLQAGYAVIFLHRHR 65

  Fly    89 SLEPFTRHFTGQQFFDMLDIADNSQSS--TIAIKPDSVDVFAPVLAKYKIARETQMILYVNFTSV 151
            |:.|::|.:|...:.|.|.:..:|.||  .:.::...:.....||.:|...:|:..:|.|.|.::
Frog    66 SMYPYSRRYTSHNWLDTLRLVPSSDSSGHQVQVEQSQLPGIVRVLQEYGSMKESGRLLPVEFNTL 130

  Fly   152 VDYMWLLRAACECLAAFEERAVLYLAAAVSDFYIPEDMMPTHKMQSGDGAPTISLQLVPKMLAPL 216
            .||:.||:||.:.:::....|:.||||||||||||...||.||:||..|...|::::|||||:||
Frog   131 SDYLHLLQAAAQAVSSLGSNAMFYLAAAVSDFYIPASEMPEHKIQSSSGPLQITMKMVPKMLSPL 195

  Fly   217 ASLWVPHAFVVSFKLETDESLLIVKARDSLNKYKHKLVIANVLQTRKHRVVFVTPTDSYELHLTR 281
            ...|.|.|||:|||||||.|:||.:||.:|..|.|::|:||||.:|:..||.||.||...|.::.
Frog   196 VKDWAPKAFVISFKLETDPSILIERARKALATYSHQVVVANVLDSRRSYVVIVTNTDEANLSVSE 260

  Fly   282 EQTLQGLEIEEPIVADVVQKHGEFISNAQQR 312
            ::...|:||||.|:.|:|.:|..||.|..::
Frog   261 QEETLGVEIEEKIIKDLVARHTSFIGNLDEK 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppcs	NP_650784.3	DFP	34..257	CDD:296430	110/224 (49%)
ppcs	NP_001072632.1	DFP	<16..240	CDD:332014	113/223 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6050
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6173
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2897
OMA	1	1.010	-	-		QHG53953
OrthoDB	1	1.010	-	-		D1292767at2759
OrthoFinder	1	1.000	-	-		FOG0004187
OrthoInspector	1	1.000	-	-		oto104647
Panther	1	1.100	-	-	LDO	PTHR12290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2934
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080