DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppcs and ppcs

DIOPT Version :9

Sequence 1:	NP_650784.3	Gene:	Ppcs / 42295	FlyBaseID:	FBgn0261285	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001038705.1	Gene:	ppcs / 561272	ZFINID:	ZDB-GENE-060512-104	Length:	320	Species:	Danio rerio

Alignment Length:	295	Identity:	142/295 - (48%)
Similarity:	199/295 - (67%)	Gaps:	1/295 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PADFEDNRSLLKEFCERHNKLQNRIVLVTSGGTTVPLEHNTVRFVDNFSAGTRGSASAEYFLDHD 78
            |:..|:.:.|:.:|.|.|.....|:||:|||||.||||..||||:||||:|.|||:|||||||..
Zfish    23 PSHVEEVKKLMADFAEHHGSAGRRVVLITSGGTKVPLESRTVRFLDNFSSGRRGSSSAEYFLDSG 87

  Fly    79 YAVIFMHRHKSLEPFTRHFTGQQFFDMLDI-ADNSQSSTIAIKPDSVDVFAPVLAKYKIARETQM 142
            |||||:|||:||.|:||.:||....|.|.: .|...:..:.:..:::...|.||.:|:..:.:.:
Zfish    88 YAVIFLHRHRSLYPYTRLYTGVNILDSLQLETDKGDTGHVLVNKEALPNIAKVLKRYQAVKVSGL 152

  Fly   143 ILYVNFTSVVDYMWLLRAACECLAAFEERAVLYLAAAVSDFYIPEDMMPTHKMQSGDGAPTISLQ 207
            :|.|.|.::.:|:.||:||.:.|::...:|:.||||||||||||...||.||:||.:|...||::
Zfish   153 LLPVEFNTLSEYLHLLKAAAQALSSIGSKAMFYLAAAVSDFYIPASEMPEHKIQSSNGPLQISMK 217

  Fly   208 LVPKMLAPLASLWVPHAFVVSFKLETDESLLIVKARDSLNKYKHKLVIANVLQTRKHRVVFVTPT 272
            :|||||:||...|.|.|||:||||||:.|:|:.|||.:|..|.|:.|:||||.||:..||.||..
Zfish   218 MVPKMLSPLVKDWAPQAFVISFKLETNPSILLEKARRALETYNHQAVVANVLDTRRGYVVVVTKD 282

  Fly   273 DSYELHLTREQTLQGLEIEEPIVADVVQKHGEFIS 307
            ..|||.||.|:..:..|||:.||.::...|.:|||
Zfish   283 TQYELLLTDEEVQKEAEIEDKIVTNLTAAHSQFIS 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppcs	NP_650784.3	DFP	34..257	CDD:296430	111/223 (50%)
ppcs	NP_001038705.1	DFP	<187..267	CDD:296430	46/79 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584096
Domainoid	1	1.000	118	1.000	Domainoid score	I5833
eggNOG	1	0.900	-	-		E1_COG0452
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6173
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2865
OMA	1	1.010	-	-		QHG53953
OrthoDB	1	1.010	-	-		D1292767at2759
OrthoFinder	1	1.000	-	-		FOG0004187
OrthoInspector	1	1.000	-	-		oto40529
orthoMCL	1	0.900	-	-		OOG6_102247
Panther	1	1.100	-	-	LDO	PTHR12290
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1904
SonicParanoid	1	1.000	-	-		X2934
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800