Protein Alignment Cyp12a4 and DIT2

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 117/515 - (22%)
• Similarity: 204/515 - (39%)
• Gaps: 95/515 - (18%)

  Fly    48 EQIPRLNMWALSMKMSMPGGKYKNMELMEMF--EAMRQDYGDIFFMPGIMGNPPFLSTHNPQDFE 110
            :.||.:..:.:.:.:..|   ....||.:::  |:| :.||.:.|..|...|   :.....:...
Yeast    31 KNIPTIPFYVVFLPVIFP---IDQTELYDLYIRESM-EKYGAVKFFFGSRWN---ILVSRSEYLA 88

  Fly   111 VVFRNEGVWPNRPGN-----YTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKN 170
            .:|::|..:. :.||     |:.|   ..|..|      .||...|..|.::|..|...|....:
Yeast    89 QIFKDEDTFA-KSGNQKKIPYSAL---AAYTGD------NVISAYGAVWRNYRNAVTNGLQHFDD 143

  Fly   171 VRLYYKKMSQVNQEFVQ-RILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKN-SNK 233
            ..::  |.:::....:: |:||.:....: .|     ...|..|:::|.|||....|.|.: .|.
Yeast   144 APIF--KNAKILCTLIKNRLLEGQTSIPM-GP-----LSQRMALDNISQVALGFDFGALTHEKNA 200

  Fly   234 ESEAL-----KLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYV-DEAIE 292
            ..|.|     ::||   .||:....|::.|.|.|       |:..:.:...:|:.:..| ||.:.
Yeast   201 FHEHLIRIKKQIFH---PFFLTFPFLDVLPIPSR-------KKAFKDVVSFRELLVKRVQDELVN 255

  Fly   293 RLDKE----AKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAK-N 352
            ....|    |...::|..|.:.       :|.|..|...:.:|:||.:.....|.:.|..||| :
Yeast   256 NYKFEQTTFAASDLIRAHNNEI-------IDYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYS 313

  Fly   353 PEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHP---LIVGNARV----LARDA 410
            .|.|.:||:||..:...|       .:.::|.|.|.:.|..|::|   .|:.....    |..:.
Yeast   314 NEWQEKLRKEVNGITDPK-------GLADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEI 371

  Fly   411 VLSGYRVPAGTYVNIVPLNALTRDEYFPQ-----ASEFLPERWLRSPKDSESKCPANELKSTNPF 470
            |     :|.|.||.......    .:.|:     |.:|.||||   ..|.|: ...|...:.|..
Yeast   372 V-----IPKGVYVGYNNFGT----SHDPKTWGTTADDFKPERW---GSDIET-IRKNWRMAKNRC 423

  Fly   471 VFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALINLP-NIPLKF 529
            ....|..|.|.|:|:::...|:.:..|.:::.|....:...|.....|....| |:.|||
Yeast   424 AVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLKF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	114/491 (23%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	110/477 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24305
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100