Protein Alignment Cyp12a4 and DWF4

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_190635.1
• Gene: DWF4 / 824229
• AraportID: AT3G50660
• Length: 513
• Species: Arabidopsis thaliana
• Alignment Length: 546
• Identity: 108/546 - (19%)
• Similarity: 200/546 - (36%)
• Gaps: 148/546 - (27%)

  Fly    61 KMSMPGGK---------------YKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQDFE 110
            :.::|.||               |....|.:..:.....||.| :...:.|.|..:|.....: .
plant    36 RFNLPPGKSGWPFLGETIGYLKPYTATTLGDFMQQHVSKYGKI-YRSNLFGEPTIVSADAGLN-R 98

  Fly   111 VVFRNEG-----VWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPW------GDFRTVVNPV 164
            .:.:|||     .:|...|                 |::|       .|      ||.
plant    99 FILQNEGRLFECSYPRSIG-----------------GILG-------KWSMLVLVGDM------- 132

  Fly   165 LMQPKNVRLYYKKMSQVNQEFVQ----RILELRDPDTLEAPDDFIDTINRWTLESV--------- 216
                      ::.|..::..|:.    |.:.|:|   :|....|:  ::.|...|:
plant   133 ----------HRDMRSISLNFLSHARLRTILLKD---VERHTLFV--LDSWQQNSIFSAQDEAKK 182

  Fly   217 -SVVALDKQLGLLKNSNKESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQ 280
             :...:.|.:..:....:|:|.||..:......:||..|.:..:.:.           :||.. :
plant   183 FTFNLMAKHIMSMDPGEEETEQLKKEYVTFMKGVVSAPLNLPGTAYH-----------KALQS-R 235

  Fly   281 EVTLAYVDEAIE--RLD---KEAKEGVVRPENE---------------QSVLEKLLKVDRKVATV 325
            ...|.:::..:|  :||   ::.:|..|:.|:|               ..:|..:|| ...::|.
plant   236 ATILKFIERKMEERKLDIKEEDQEEEEVKTEDEAEMSKSDHVRKQRTDDDLLGWVLK-HSNLSTE 299

  Fly   326 MAMD----MLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNK----NSEFTEASMKNV 382
            ..:|    :|.||.:|:|......:..|...|:....||||.:::...|    .||......|.:
plant   300 QILDLILSLLFAGHETSSVAIALAIFFLQACPKAVEELREEHLEIARAKKELGESELNWDDYKKM 364

  Fly   383 PYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVP-LNALTRD-EYFPQASEFLP 445
            .:.:..|.|:.||..::....|...:|....||.:|:|.  .::| ::|:..| ..:.|.:.|.|
plant   365 DFTQCVINETLRLGNVVRFLHRKALKDVRYKGYDIPSGW--KVLPVISAVHLDNSRYDQPNLFNP 427

  Fly   446 ERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYP 510
            .||.:....:.|.  .:...||....::|||.|||:|.|..:.::|:.:....|:..||.|....
plant   428 WRWQQQNNGASSS--GSGSFSTWGNNYMPFGGGPRLCAGSELAKLEMAVFIHHLVLKFNWELAED 490

  Fly   511 TENAFRSALINLPNIPLKFKFIDLPN 536
            .:             |..|.|:|.||
plant   491 DK-------------PFAFPFVDFPN 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	98/500 (20%)
DWF4	NP_190635.1	PLN02500	29..513	CDD:215276	108/546 (20%)