Protein Alignment Cyp12a4 and zgc:136333

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_073768315.1
• Gene: zgc:136333 / 723999
• ZFINID: ZDB-GENE-060616-143
• Length: 542
• Species: Danio rerio
• Alignment Length: 526
• Identity: 150/526 - (28%)
• Similarity: 253/526 - (48%)
• Gaps: 53/526 - (10%)

  Fly    24 KRWQTNVATAEAREDSEWLQAKPFEQIPRLNMWALSMKMSMPGGKYKNMELMEMFEAMRQDYGDI 88
            :|...|.|.|.........:.|....:|.:.::.:..:|...|  |.| .:.|:....:|.||.:
Zfish    48 RRAAGNAAAASVSVQDGHRKLKTEADLPEIKIFTMLYQMLFKG--YLN-SIHELQIYQKQVYGPL 109

  Fly    89 FFMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKP 153
            ..:..  ||...:|..:.:..|.:.|.:..:|.| |..||.....:.|...|    |....:|:.
Zfish   110 SKINS--GNLQGISISSVELLEELLRKDEKYPCR-GYMTLWTEHRDLRGIGY----GPFTEEGEK 167

  Fly   154 WGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRD-PDTLEAPDDFIDTINRWTLESVS 217
            |...|.|:|..::.||:...|...::.|..:|::||..||: ..|.:...:..:.:.|::||.::
Zfish   168 WYKLRAVLNKRMLHPKDSLQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLEGIA 232

  Fly   218 VVALDKQLGLLKNSNKE--SEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQ 280
            .:..:.::|.|:   ||  .|..:..:.:.:.|..|:.:.:.|: |.....|..::.:...|||.
Zfish   233 SILFETRIGCLE---KEIPVETQEFINSIAQMFTYSMHVALLPN-WTRNYFPFWQKYIDGWDGIF 293

  Fly   281 EVTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLL-------KVDRKVATVMAMDMLMAGVDTT 338
            :.....:|..:|.:.|       |.:..|.|..:.|       |:..|.......::|:||||||
Zfish   294 KFGTKMIDMKMEAIQK-------RVDTNQEVAGEYLTYLLSSGKMSSKDVYGSVSELLLAGVDTT 351

  Fly   339 SSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNA 403
            |:|....|..|:|:|..|..|.:||.|||.:.... |...:.::|:|:|.|||:.||:|::..|:
Zfish   352 SNTMLWALYLLSKDPAAQETLYQEVTKVLKDDRIP-TAEEVNSMPFLKAVIKETLRLYPVVPVNS 415

  Fly   404 RVLARDAVLSG-YRVPAGTYVNIVPLNALTRDE-YFPQASEFLPERWLRSPKDSESKCPANELKS 466
            |::|...|:.| |..|..|..|:... |::.|| .||:..:|.||||||   |..::
Zfish   416 RLIAETEVVIGEYFFPKKTTFNLCHY-AISHDEKVFPEPQKFKPERWLR---DGRTR-------- 468

  Fly   467 TNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPT----ENAFRSALINLPNIPL 527
            .|||..:|||||.|.|||:||.|:|:.|..||||:.|.:..: ||    :..|||.|:  ||..:
Zfish   469 PNPFGSIPFGFGVRACVGRRIAELEMHLALARLIKLFEMRPD-PTVGEVKANFRSVLV--PNKKV 530

  Fly   528 KFKFID 533
            ...|::
Zfish   531 NLHFVE 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	138/461 (30%)
zgc:136333	XP_073768315.1	None