Protein Alignment Cyp12a4 and Cyp6a22

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 405
• Identity: 104/405 - (25%)
• Similarity: 182/405 - (44%)
• Gaps: 45/405 - (11%)

  Fly   107 QDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNV 171
            ||| ..|.:.|           :||.|  |.|...|.:..|  .|..|...|..::|.....| :
  Fly    95 QDF-ANFEDRG-----------MYHNE--RDDPLTGHLFRI--DGPKWRPLRQKMSPTFTSAK-M 142

  Fly   172 RLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKESE 236
            :..:..:.:|.:|..|...||.| :.:....:..|.:.|:|.:.:...|...:...|:|...|..
  Fly   143 KYMFPTVCEVGEELTQVCGELAD-NAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFA 206

  Fly   237 ALKLFHYLDEFFIVSIDLEMKPSPWRYIKT-PKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKE 300
            .:....:.:......:|        .:|:: |::.|.:|.....|::|..||....|.:.:..::
  Fly   207 IMGRRAFSERRHCKLVD--------GFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQ 263

  Fly   301 GVVRPENEQSVLEKLLKVDRKVATVMAMDMLM--AGVDTTSSTFTALLLCLAKNPEKQARLREEV 363
            |:||.:....::|...:.:..:..:.|...:.  ||.||::||....|..|||.|..||:||||:
  Fly   264 GIVRSDFMNLLIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEI 328

  Fly   364 MKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYR---VPAGTYVNI 425
            .:.|...|.|||..||:.:.|:...|.|:.|.:|::....|:........|.|   :..|..: :
  Fly   329 DQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQML-L 392

  Fly   426 VPLNALTRD-EYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVE 489
            :|:..:..| ..:|:..:|:|||:|           |::|.......:||||.|||.|:|.|..:
  Fly   393 IPVYGIHHDPALYPEPHKFIPERFL-----------ADQLAQRPTAAWLPFGDGPRNCIGMRFGK 446

  Fly   490 MELELGTARLIRNFN 504
            |:..:|...|:|||:
  Fly   447 MQTTIGLVSLLRNFH 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	104/405 (26%)
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	104/405 (26%)