Protein Alignment Cyp12a4 and cyp27c1

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001011341.1
• Gene: cyp27c1 / 496805
• XenbaseID: XB-GENE-6257635
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 485
• Identity: 131/485 - (27%)
• Similarity: 243/485 - (50%)
• Gaps: 64/485 - (13%)

  Fly    74 LMEMFEAMRQDYGDIF---FMPGIMGNPPFLSTHNPQDFEV-VFRNEGVWPNRPGNYTLLYHREE 134
            :.|:.:...:.||.||   |      .|.|:.:...:|... |.|.|...|.|....:  :|  |
 Frog    22 IQEIQQKHARQYGRIFKSHF------GPQFVVSIADKDMVAQVLRAERDAPQRANMES--WH--E 76

  Fly   135 YRKDFYQG-VMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELR--DPD 196
            ||:  .:| ..|:|..:|:.|.:.|:|:...:::|::|.:|...:::|.::.|:||.:||  :.|
 Frog    77 YRE--LRGRSTGLISAEGEKWLNMRSVLRQKILRPRDVAMYSGGVNEVVEDLVKRIRKLRVQESD 139

  Fly   197 TLEAPDDFIDTIN----RWTLESVSVVALDKQLGLL-----KNSNKESEALKLFH--YLDEFFIV 250
            .|.     :..:|    ::::|:::.:..:.:||.|     :.:.:..|||:|..  :....:..
 Frog   140 GLT-----VTNVNDLYFKYSMEAIATILYECRLGCLDDQIPQQTKEYIEALELMFSMFKTTMYAG 199

  Fly   251 SIDLEMK---PSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPENEQSVL 312
            :|...::   |.|||        ...|:.||:.:.:..:||:.:.:::.:.::|   .|.:..||
 Frog   200 AIPKWLRPLIPKPWR--------EFCRSWDGLFKFSQIHVDDRLRQIESQLEKG---EEVQGGVL 253

  Fly   313 EKLL---KVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEF 374
            ..||   ::|.:.......:||:|||||||.|.:.....|||||..|..:.:::::.. .|:...
 Frog   254 THLLLSKELDLEEIYANMTEMLLAGVDTTSFTLSWATYLLAKNPGIQEAVYQQIVQNF-GKDQVP 317

  Fly   375 TEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQ 439
            |...:..:|.:||.:||:.||.|::.||.||...|.|:.||.:|.||.:.:...:.....|.||.
 Frog   318 TAEDVPKMPLVRAVVKETLRLFPVLPGNGRVTQDDLVVGGYFIPKGTQLALCHYSTSYDAECFPA 382

  Fly   440 ASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFN 504
            |.||.||||:||          ..|:....|..:|||:|.|.|:|:|:.|:|:.|...:|::||.
 Frog   383 AEEFRPERWIRS----------GNLERKENFGSIPFGYGIRSCIGRRVAELEMHLLLIQLLQNFE 437

  Fly   505 VEFNYPTENAF-RSALINLPNIPLKFKFID 533
            ::.:..|.... ::..:..|...:..:|:|
 Frog   438 IKPSPQTTTVLPKTHGLLCPGGKINVRFVD 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	129/481 (27%)
cyp27c1	NP_001011341.1	p450	2..457	CDD:306555	128/473 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010