Protein Alignment Cyp12a4 and dib

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 144/504 - (28%)
• Similarity: 245/504 - (48%)
• Gaps: 50/504 - (9%)

  Fly    44 AKPFEQI--PRLNMWALSMKMSMPG-GKYKNMELMEMFEAMRQDYGDIF---FMPGIMGNPPFLS 102
            |||::.|  ||......::...:|| |.|..:.|.:..:...:.||.|.   .:||    ...:.
  Fly    18 AKPYQAIPGPRGPFGMGNLYNYLPGIGSYSWLRLHQAGQDKYEKYGAIVRETIVPG----QDIVW 78

  Fly   103 THNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQ 167
            .::|:|..::. ||...|.|..:..|..:|:. |.|.|: ..|::||.|..|...|..|...|..
  Fly    79 LYDPKDIALLL-NERDCPQRRSHLALAQYRKS-RPDVYK-TTGLLPTNGPEWWRIRAQVQKELSA 140

  Fly   168 PKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLG--LLKN 230
            ||:||.:.:::..|.:||::.:.|.|:...:    |.:..:.|..||...::....:|.  ..:.
  Fly   141 PKSVRNFVRQVDGVTKEFIRFLQESRNGGAI----DMLPKLTRLNLELTCLLTFGARLQSFTAQE 201

  Fly   231 SNKESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLD 295
            .:..|.:.:|....:......:..:.....||:::||..::|.:|...::.|.|..|:|.:
  Fly   202 QDPRSRSTRLMDAAETTNSCILPTDQGLQLWRFLETPSFRKLSQAQSYMESVALELVEENV---- 262

  Fly   296 KEAKEGVVRPENEQSVLEKLLK---VDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQA 357
               :.|.|    ..|::...:|   :||......|.|:|:||:||||.....||..:|:|||.|.
  Fly   263 ---RNGSV----GSSLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQ 320

  Fly   358 RLREEVMKVLPNKNSEFT-EASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGT 421
            :|.||..:|||:...|.: :|...::.|.||.:|||.||:|:.||..|:|.:||:.|||.||.||
  Fly   321 KLHEEARRVLPSAKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGRILNQDAIFSGYFVPKGT 385

  Fly   422 YVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKR 486
            .|....:.|...:::|.....|.|:|||:            ...:.||::.||||.|.|.|:.:|
  Fly   386 TVVTQNMVACRLEQHFQDPLRFQPDRWLQ------------HRSALNPYLVLPFGHGMRACIARR 438

  Fly   487 IVEMELELGTARLIRNFNVEFN-YPTENAFRSALINLPNIPLKFKFIDL 534
            :.|..:.:...||:|.:.:.:: ...|...::.|||.|:.|:   .|||
  Fly   439 LAEQNMHILLLRLLREYELIWSGSDDEMGVKTLLINKPDAPV---LIDL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	131/468 (28%)
dib	NP_524810.2	p450	25..446	CDD:299894	128/454 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4812
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	7	6.870