Protein Alignment Cyp12a4 and cyp27b1

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001006907.1
• Gene: cyp27b1 / 448754
• XenbaseID: XB-GENE-942527
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 455
• Identity: 125/455 - (27%)
• Similarity: 219/455 - (48%)
• Gaps: 61/455 - (13%)

  Fly    99 PFLSTH--NPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQG-VMGVIPTQGKPWGDFRTV 160
            |.|:.|  .|...|.|.|.||..|.|..    |...::||:  .:| ..|::..:|:.|..||::
 Frog    86 PILTVHVAEPSLIEQVLRQEGKHPIRSD----LSSWKDYRQ--CRGHSYGLLTAEGEEWQQFRSI 144

  Fly   161 VNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQL 225
            :...:::||.|..|...::.|..:.:::|...|..:......|.......:.||.:|.|..:.::
 Frog   145 LGKHMLKPKEVEAYSDVLNDVVGDLIKKINYQRSQNQNNVVKDIAKEFYMFGLEGISSVLFESRI 209

  Fly   226 GLLKNS-NKESEALKLFHYLDEFFIVSIDLEMKP--------SPWRYIKTPKLKRLMRALDGIQE 281
            |.|:.: .||:|  |....::..|::::.....|        .||        ::...:.|.:..
 Frog   210 GCLEPTVPKETE--KFIQSINTMFVMTLLTMAMPKFLHKIFRKPW--------QKFCESWDYMFA 264

  Fly   282 VTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLL-------KVDRKVATVMAMDMLMAGVDTTS 339
            ....::|:.::.:.::..:|       :.|..|.|       |:..|.......::|:|||||.|
 Frog   265 FAKGHIDKRMKDVAQKLAQG-------EKVEGKYLTYYLAQEKIPMKSIYGNVTELLLAGVDTIS 322

  Fly   340 STFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNAR 404
            ||.:..|..||::|:.|:.:..||.::|..|... :.:.:..:|.|:|.:||..||:|:|.||||
 Frog   323 STLSWSLYELAQHPDIQSAVYSEVEEILQGKQIP-SPSDVARMPLLKAVVKEVLRLYPVIPGNAR 386

  Fly   405 VLA-RDAVLSGYRVPAGTYVNIVPLNALTRDE-YFPQASEFLPERWLRSPKDSESKCPANELKST 467
            |:| ||..:..|.:|..|.:.:... |.:||| .|...:||.|:|||:. :|:.
 Frog   387 VVADRDIQVGDYIIPKKTLITLCHY-ATSRDENVFSNPNEFQPDRWLKK-EDTH----------- 438

  Fly   468 NPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAF---RSALINLPNIPLKF 529
            :|:..||||||.|.|:|:||.|:|:.|..||::.:|.|:...|.....   |:.|:....|.|:|
 Frog   439 HPYASLPFGFGKRSCIGRRIAELEVYLALARILSHFEVKPEQPGSLVMPMTRTLLVPEKEINLQF 503

  Fly   530  529
             Frog   504  503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	125/455 (27%)
cyp27b1	NP_001006907.1	p450	45..503	CDD:365848	124/453 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.980