Protein Alignment Cyp12a4 and Cyp4e1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 461
• Identity: 108/461 - (23%)
• Similarity: 204/461 - (44%)
• Gaps: 75/461 - (16%)

  Fly    73 ELMEMFEAMRQDYG-DIF-FMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEY 135
            |::..|.....:|| |.| :..|...|   :...||:..|.:..::          ||:...:.|
  Fly    54 EILNRFFGWWHEYGKDNFRYWIGYYSN---IMVTNPKYMEFILSSQ----------TLISKSDVY 105

  Fly   136 RKDFYQGVMGVIPTQGKPWGDFRTVVNPV----LMQPKNVRLYYKKMSQVNQEFVQRILELRDPD 196
            ........:|::.:.|..|...|.::.|.    ::|.     :::.|::.:.:|:.::.::.|..
  Fly   106 DLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQD-----FHEVMNENSTKFIDQLKKVADGG 165

  Fly   197 TLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNS--NKESEALKLFHYLDEFFIVSIDLEMKP- 258
            .:   .||.:..:..||:    |..|..:|:..|:  |:.|..::.|.      .::..::|:.
  Fly   166 NI---FDFQEEAHYLTLD----VICDTAMGVSINAMENRSSSVVQAFK------DITYTIKMRAF 217

  Fly   259 SPWRYIK-----TPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPE---NEQSVLEKL 315
            |||:..|     .|:.....:.|..:|:.|...:.:.||......:.|:...|   .:.:.|:.|
  Fly   218 SPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTL 282

  Fly   316 L--KVDRKVATVMAM-----DMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLP----N 369
            |  |||.:..|...:     ..:..|.|||:|.....:..|:::|::|.:|..|...|:.    .
  Fly   283 LSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLG 347

  Fly   370 KNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRD 434
            :::.|.|.|  .:.:|...|||:|||:|.:....|...:|.|:.|..||.||.:|:..|.....|
  Fly   348 RDATFQEIS--TMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYND 410

  Fly   435 EYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARL 499
            ..|....:|.|||:.|              :...||.::||..|||.|:|::...:|::...:::
  Fly   411 RVFKDPHKFQPERFDR--------------EKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKI 461

  Fly   500 IRNFNV 505
            ||||.|
  Fly   462 IRNFEV 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	106/452 (23%)
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	104/447 (23%)