Protein Alignment Cyp12a4 and Cyp4c3

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 479
• Identity: 118/479 - (24%)
• Similarity: 183/479 - (38%)
• Gaps: 144/479 - (30%)

  Fly    96 GNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTV 160
            |..|.:....|:..|.:. |...:.|:..:|..|:.        :.| .|::.:..:.|...|.:
  Fly   103 GTAPRVLLFEPETVEPIL-NSQKFVNKSHDYDYLHP--------WLG-EGLLTSTDRKWHSRRKI 157

  Fly   161 VNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINR--------------- 210
            :.|.                    |..:||           |||||..|.
  Fly   158 LTPA--------------------FHFKIL-----------DDFIDVFNEQSAVLARKLAVEVGS 191

  Fly   211 -----------WTLESVSVVALDKQLGLLKNSNKESEALKLFH-------------YLDEFFIVS 251
                       .||:.|...|:.::  :...||.|||.:|..:             :|...||.|
  Fly   192 EAFNLFPYVTLCTLDIVCETAMGRR--IYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFS 254

  Fly   252 IDLEMKPSPWRYIKT-------------PKLKRLM--------RALDGIQEV----TLAYVDEAI 291
            :..|.|... .||.|             .:|..|.        .|.|...:|    .||::|..|
  Fly   255 LTAEYKLHQ-SYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLI 318

  Fly   292 ERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQ 356
            :    .:|||.|. .||.        :..:|.|.|     ..|.||||:..:..|..|..:||.|
  Fly   319 D----ASKEGTVL-SNED--------IREEVDTFM-----FEGHDTTSAAISWTLFLLGCHPEYQ 365

  Fly   357 ARLREEVMKVLPNKNSEFTEASMKN---VPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVP 418
            .|:.||:..:..:...  |.|:|||   :.||..|||:|.||.|.:...||::..|..:.|..||
  Fly   366 ERVVEELDSIFGDDKE--TPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVP 428

  Fly   419 AGTYVNIVPLNALTRD-EYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMC 482
            |||.. |:...||.|: ..||:..:|.|:.:|          |.| ....:||.::||..|||.|
  Fly   429 AGTQA-IIMTYALHRNPRVFPKPEQFNPDNFL----------PEN-CAGRHPFAYIPFSAGPRNC 481

  Fly   483 VGKRIVEMELELGTARLIRNFNVE 506
            :|::...:|.:...:.::|.:.:|
  Fly   482 IGQKFAILEEKAVISTVLRKYKIE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	118/479 (25%)
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	118/479 (25%)