Protein Alignment Cyp12a4 and Cyp12a5

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 536
• Identity: 408/536 - (76%)
• Similarity: 472/536 - (88%)
• Gaps: 0/536 - (0%)

  Fly     1 MLKVRSALSLIQSQKATLSLATQKRWQTNVATAEAREDSEWLQAKPFEQIPRLNMWALSMKMSMP 65
            |||.|.||:::||||..:..|:|:||||||.|||.|.|.|||||||||:||:.|:.:|..|.::|
  Fly     1 MLKGRIALNILQSQKPIVFSASQQRWQTNVPTAEIRNDPEWLQAKPFEEIPKANILSLFAKSALP 65

  Fly    66 GGKYKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLY 130
            ||||||:|:|||.:|:|||||:|.|:||:||....:.||||:|||||||||||||.|||:..|.|
  Fly    66 GGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRY 130

  Fly   131 HREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDP 195
            ||..|||||:.||.|:||:|||.|||||::||||||||||||||:|||||||||||:.|.|:||.
  Fly   131 HRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKEIRDA 195

  Fly   196 DTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKESEALKLFHYLDEFFIVSIDLEMKPSP 260
            .|.|.|.:|::||||||||||||||||||||||:.|.|.|||.|||.||||||:.|.|||||||.
  Fly   196 STQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFKYLDEFFLHSADLEMKPSL 260

  Fly   261 WRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATV 325
            |||.|||.||:::|.:|.:|||||.|||||||||:|||||||||||:||||||||||||:|||||
  Fly   261 WRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSVLEKLLKVDKKVATV 325

  Fly   326 MAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIK 390
            |||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||
  Fly   326 MAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEASMKNVPYLRACIK 390

  Fly   391 ESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDS 455
            ||||::||::||||.|.||:|:|||||||||.|:::|:|:|..:||||:.:|||||||||:..||
  Fly   391 ESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEYFPKPTEFLPERWLRNASDS 455

  Fly   456 ESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALI 520
            ..|||||:||:.|||||||||||||||||||||||||||||||||||||||||:.|:||||||||
  Fly   456 AGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAFRSALI 520

  Fly   521 NLPNIPLKFKFIDLPN 536
            |||||||||||.|:||
  Fly   521 NLPNIPLKFKFTDVPN 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	359/458 (78%)
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	354/449 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445001
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	1	0.900	-	-		OOG6_100895
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	11	10.800