Protein Alignment Cyp12a4 and Cyp313a4

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 112/528 - (21%)
• Similarity: 209/528 - (39%)
• Gaps: 114/528 - (21%)

  Fly    52 RLNMWALSMKMSMPGG---------KYKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQ 107
            |...:.|::|:..|.|         ..:..:::..|......:|...|  ..:|..||:...:||
  Fly    22 RRRFYLLTLKIPGPLGYPILGMAHWLMRREDILNAFGCFLDKHGPTIF--SWLGPIPFMIVSDPQ 84

  Fly   108 DFEVVFR-----NEGVWPNRPGNYTLLYHREEYRKDFYQGV-----MGVIPTQGKPWGDFRTVVN 162
            ..:.:|.     |:|:                    .|:.|     :|:...:...|...|.::|
  Fly    85 VVQDIFTSPHCVNKGI--------------------IYKAVDDGAGVGLFSLKDPRWSIHRKLLN 129

  Fly   163 PVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGL 227
            |..    ..::....:...|:| ...:|:..:|...:...|.|..:..:||.    :|....:|
  Fly   130 PAF----GHKVLLSFLPIFNRE-TALLLDQLEPLQDDGEKDLIPLLQSFTLG----IATQTTMG- 184

  Fly   228 LKNSNKESEALKLFHYLDEF-FIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQ--------EVT 283
              :..|:.|:.:....|..: .|:....:|..|||..      .|..|.|.|.:        |:.
  Fly   185 --SDVKDEESFRSNSLLGRYQCILETMTDMCFSPWLN------SRFCRQLAGKESHYYQAKTEIR 241

  Fly   284 LAYVDEAIERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGV------------- 335
             .::.:.|||  |.|       |:|...|..:...|:.:...:..|::..||
  Fly   242 -QFIRKIIER--KLA-------EDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDESNII 296

  Fly   336 -----DTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNS-EFTEASMKNVPYLRACIKESQR 394
                 :||::.....|:.||..||.|.|..||:..:.||... :.:.|..:.:.||...:.||.|
  Fly   297 VFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMR 361

  Fly   395 LHPLIVGNARVLARDAVLS-GYRVPAGTYVNIVPLNALTRDE--YFPQASEFLPERWLRSPKDSE 456
            :.|.:...:|..::|..|| |..||.|..: .:.:..:.|.:  :.|.|..|.|:.:|
  Fly   362 VIPPVPVVSRQTSQDLKLSNGIVVPKGVQI-AIDIYHMHRSKKIWGPDAETFNPDHFL------- 418

  Fly   457 SKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAF--RSAL 519
               |.| ::..:|:.::||..|.|.|:|.|...:..::..|:|:||:..:.::|.||.:  ....
  Fly   419 ---PHN-IQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDIT 479

  Fly   520 INLPNIPL 527
            :.|.::||
  Fly   480 MKLKSVPL 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	106/489 (22%)
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	106/485 (22%)