Protein Alignment Cyp12a4 and Cyp12e1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 532
• Identity: 225/532 - (42%)
• Similarity: 315/532 - (59%)
• Gaps: 32/532 - (6%)

  Fly    20 LATQKRWQTN----------------VATAEAREDSEWLQAKPFEQIPRLNMWALSMKMSMPGGK 68
            |:||  |..|                .|||...|     :|||:..||..:...| ::..:|||.
  Fly     2 LSTQ--WNANKQISRQIYQLCRGLAQKATAVNLE-----EAKPYADIPGPSKLQL-IRAFLPGGL 58

  Fly    69 YKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHRE 133
            |||:.:.|||..|.:.||.||.||.:.|....| |.||||:||:|||||.:|.|.....:.|.:.
  Fly    59 YKNLPVHEMFLDMNRQYGSIFRMPSVAGTDLVL-TMNPQDYEVIFRNEGQYPYRRSFEVMDYFKR 122

  Fly   134 EYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTL 198
            .:|::.:.|..|:....|..||..||.|||:|:||:|.:||...:.||:.||::||..:|||.|.
  Fly   123 VHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQ 187

  Fly   199 EAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKESEALKLFHYLDEFFIVSIDLEMKPSPWRY 263
            |.||||...|....:||:..|||:..||||.......:..||...|.:...:...|::.|:.|:|
  Fly   188 EMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLALQDVVELGFQLDIMPAFWKY 252

  Fly   264 IKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPEN-EQSVLEKLLKVDRKVATVMA 327
            :..|..|:|||:||.|.:....::..|::|::::||.|.:.... |.|:||||.:.||:.|.::|
  Fly   253 LPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTLNEIGLETSLLEKLARFDRQTAVIIA 317

  Fly   328 MDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKES 392
            ||:|.||.|.|..|...:|..|:|:|:|||||.||:..:||||:|..|..:|:|:|||||||||.
  Fly   318 MDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIENMRNLPYLRACIKEG 382

  Fly   393 QRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYF-PQASEFLPERWLRSPKDSE 456
            .|::|:..|..|.:..|.|||||||.|||.|.|.....:...|.| |:..||:||||||...:|.
  Fly   383 IRMYPIGPGTLRRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLRDESNSH 447

  Fly   457 SKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALIN 521
            ...     ::..||::||||||||.|.|||||:|.||:..:||:|||.:.|:||.||||::....
  Fly   448 LVG-----ETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNFKIGFDYPIENAFKAQFFV 507

  Fly   522 LPNIPLKFKFID 533
            .||||.|||||:
  Fly   508 QPNIPFKFKFIE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	195/447 (44%)
Cyp12e1	NP_650003.4	CYP24A1-like	73..514	CDD:410677	195/446 (44%)