Protein Alignment Cyp12a4 and Cyp313b1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_649807.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 120/534 - (22%)
• Similarity: 213/534 - (39%)
• Gaps: 122/534 - (22%)

  Fly    56 WALSMKMSMP----GGKYKNME--LMEMFEAMRQDYGDIFFMPGI--MGNPPFLSTHNPQDFEVV 112
            |.|...:..|    |.:..|.|  |..|....||     |..|.|  ||...||..::|...|.:
  Fly    30 WQLRGPIGWPLIGMGLQMMNPETFLQYMDGLSRQ-----FKAPFISWMGTSCFLYINDPHSVEQI 89

  Fly   113 FR-----NEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIP----TQGKP-WGDFRTVVNPVLMQ 167
            ..     |:|                    |||:.:...|.    |...| |...|.::||..
  Fly    90 LNSTHCTNKG--------------------DFYRFMSSAIGDGLFTSSSPRWHKHRRLINPAF-- 132

  Fly   168 PKNVRLYYKKMSQVNQEFVQRILEL---RDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLK 229
            .:.:...:..:.....|.:.:.|||   :....||    ....:.:..||:.....:.|::..
  Fly   133 GRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLE----IYQILKKIVLEAACQTTMGKKMNF-- 191

  Fly   230 NSNKESEALKLFHYLDEFFIVSIDLEMKPSPWRY----IKTPKLKRLMRALDGIQEVTLAYVDEA 290
               :...:|.:|...:.  :..:.::...|||.|    .:...|.||.:.:.||   ...::::.
  Fly   192 ---QHDGSLCIFKAYNG--LTEVCVKRMLSPWLYPDLIYRRSGLFRLQQKVVGI---LFGFIEQL 248

  Fly   291 IERL----------DKEAKEGVVRPENEQSVLEKLLK-VDRKVATVMAMDM-------LMAGVDT 337
            :|.:          |::..|..:|.:::...:|::.: |:|  ..:...|:       :.|..:|
  Fly   249 LEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVER--GQLSWQDVRDEANVTIAATFET 311

  Fly   338 TSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLH---PLI 399
            ||:.....:||||.:|..|.:|.:|::..|| .:.:.....::.:.|....|.|:.||.   |::
  Fly   312 TSTALYFTILCLAMHPCYQEKLHKELVTELP-PSGDINLEQLQRLEYTEMVINEAMRLFAPVPMV 375

  Fly   400 VGNARVLARDAVL----SGYRVPAGTYVNIVPLNALTRDE--YFPQASEFLPER--WLRSPKDSE 456
            :.:|   .:|..|    ..:.:|.||.:.|...| :.|||  :.|.:..:.|:.  .|.||:
  Fly   376 LRSA---DQDIQLKRGDGEFLIPRGTQIGIDIYN-MQRDERVWGPLSRTYNPDAHFGLDSPQ--- 433

  Fly   457 SKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALIN 521
                      .:.|.|:||..|.|||:|.|..:|.::|..||:.|::.:.    ||......|:.
  Fly   434 ----------RHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRIS----TEARLEELLVK 484

  Fly   522 LPNIPLKFKFIDLP 535
             .||.||.|  |.|
  Fly   485 -GNISLKLK--DYP 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	107/493 (22%)
Cyp313b1	NP_649807.1	CYP313-like	66..498	CDD:410680	109/493 (22%)