Protein Alignment Cyp12a4 and Cyp12c1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 241/501 - (48%)
• Similarity: 333/501 - (66%)
• Gaps: 14/501 - (2%)

  Fly    38 DSEWLQAKPFEQIPRLNMWALSMKMSMPGGKYKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLS 102
            :|||..||||.::|....|.| .:....||:|..:.:.::....::.:|||..:||:.|.|..:.
  Fly    32 ESEWEGAKPFTELPGPTRWQL-FRGFQKGGEYHQLGMDDVMRLYKKQFGDICLIPGLFGMPSTVF 95

  Fly   103 THNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQ 167
            |.|.:.||.|:|.||.||.|.|...::::|.:.:.:|::..||:. ..|..||..|:.|||||||
  Fly    96 TFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLF-GNGAEWGKNRSAVNPVLMQ 159

  Fly   168 PKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSN 232
            .:||.:|.|.|.:||::||.||.|:||.::.|.|.||::|||..|.|||:.||||::||||:.:|
  Fly   160 HRNVAIYLKPMQRVNRQFVNRIREIRDKESQEVPGDFMNTINHLTFESVATVALDRELGLLREAN 224

  Fly   233 KESEALKLFH----YLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIER 293
            ...||.|||.    .:|.||    ||.::||.:|||.||..|:..||:|.|.:....||::||||
  Fly   225 PPPEASKLFKNIEVLMDSFF----DLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIER 285

  Fly   294 LDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQAR 358
            :|:::.:|  ...:.:||||:||::|||:|.||||||||.||||||:..:.:||.||||||||.|
  Fly   286 IDRKSSQG--DSNDHKSVLEQLLQIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPEKQQR 348

  Fly   359 LREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYV 423
            |||||:..|.:.:||||...||::|||||.||||.||:|:..||||....|.||.|||:|.||.:
  Fly   349 LREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRIPKGTKL 413

  Fly   424 NIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIV 488
            .:.....|..|..:|:|.||:||||||...|.:|....|  |..|.|::||||||||||||||||
  Fly   414 LMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMN--KDLNAFIYLPFGFGPRMCVGKRIV 476

  Fly   489 EMELELGTARLIRNFNVEFNYPTENAFRSALINLPNIPLKFKFIDL 534
            ::|:||..|.|:|||::|:||.||..::...:..|||||||||.||
  Fly   477 DLEMELTVANLVRNFHIEYNYSTEKPYKCRFLYKPNIPLKFKFTDL 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	221/449 (49%)
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	221/448 (49%)