Protein Alignment Cyp12a4 and Cyp312a1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 445
• Identity: 113/445 - (25%)
• Similarity: 192/445 - (43%)
• Gaps: 76/445 - (17%)

  Fly    95 MGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVM--GVIPTQGKPWGDF 157
            ||...:|...||:|.:.:...:          .||....:||  .::..:  |:..:..:.|...
  Fly    78 MGTKLYLVDCNPKDIQALCSAQ----------QLLQKTNDYR--VFENWLCEGLFTSGFEKWSHR 130

  Fly   158 RTVVNPVL--MQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVA 220
            |.:|.|..  ...|.....::|.|::....|.:..|..|      ..||:..|:.:||:::...|
  Fly   131 RKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGD------QIDFLQLISCFTLDTICETA 189

  Fly   221 LDKQLGLLKNSNKESEALKLFHYLD--EFFIVSIDLEMKPSPWR----YIKTPKLKR---LMRAL 276
            |...:|  ..|:.:||      |||  :..:|.||..:|...:|    :.:|...||   |::.|
  Fly   190 LGVSVG--SQSSAKSE------YLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTL 246

  Fly   277 DGIQEVTLAYVDEAIERLDKEAK-----------EGVVRPENEQSVLEKLL---KVDRKVATVMA 327
            .|..|   ..:.:.|:.::::|:           :||.|   ....|:.||   ..|.|..||..
  Fly   247 HGFTE---GIIQKRIDEINQDAENRNYQSSDAELDGVKR---TLCFLDTLLLSKGPDGKPLTVKD 305

  Fly   328 M-----DMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSE-FTEASMKNVPYLR 386
            :     .::..|.|.|::|....:..:..:||.|.|.||||..|.....|| .:...::.:.:|.
  Fly   306 IREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLE 370

  Fly   387 ACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRS 451
            |||||:.|::|.....||....:..::.:.:|.|:.|.|.|:......::||....|.|:||...
  Fly   371 ACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIG 435

  Fly   452 PKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVE 506
               :|.|..|.        .|:||..|.|.|:|:|...:.|::..|.|:|||..|
  Fly   436 ---AEPKIEAT--------TFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	113/445 (25%)
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	113/445 (25%)