Protein Alignment Cyp12a4 and shd

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001261843.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 140/478 - (29%)
• Similarity: 227/478 - (47%)
• Gaps: 35/478 - (7%)

  Fly    68 KYKNMELMEMFEAMRQDYGDIFF--MPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLY 130
            :||..:|.|::..:.:.||||..  ||   .|.|.:..:|..|.|.|.:....:|.||....::.
  Fly    83 RYKMTKLHEVYADLNRQYGDIVLEVMP---SNVPIVHLYNRDDLEKVLKYPSKYPFRPPTEIIVM 144

  Fly   131 HREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDP 195
            :|:. |.|.|..| |::..||..|...|:.:...:..|:.::.:...::.|..:|::.:...|||
  Fly   145 YRQS-RPDRYASV-GIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDP 207

  Fly   196 DTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKESEAL-KLFHYLDEFFIVSIDLEMKPS 259
            |||..| :|.:..|...||:|..:.|.:::|.|....|:.:.: :|...:.:.||...|......
  Fly   208 DTLVVP-NFEELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLG 271

  Fly   260 PWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLLKV------ 318
            .|:|..|...:...||.|.|.:|....:|..:|.|.|.|..........:|:...:|::
  Fly   272 LWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDDEAAGLRSIFLNILELKDLDIR 336

  Fly   319 DRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVP 383
            |:|.|.:   |.:.||::|.::|...:|..:..:|....|:..|..:.   :::...:.::.|..
  Fly   337 DKKSAII---DFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCEY---RDTNILQDALTNAT 395

  Fly   384 YLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERW 448
            |.:|||:||.||.|.....||:|..|..||||.:.|||.|....:.|..:|..|..|.:|.||||
  Fly   396 YTKACIQESYRLRPTAFCLARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERW 460

  Fly   449 LRSPKDSESKCPANE---LKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYP 510
            :.         ||.|   :...|..:.:|||.|.|.|.|||.||||:.|..|:::..|:|.|..|
  Fly   461 ID---------PATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVKP 516

  Fly   511 TENAFRSALINLPNIPLKFKFID 533
            .|..|...|  .|..||..:..|
  Fly   517 LETEFEFLL--APKTPLSLRLSD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	137/470 (29%)
shd	NP_001261843.1	p450	63..528	CDD:299894	136/467 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4812
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870