Protein Alignment Cyp12a4 and Cyp4d20

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 459
• Identity: 111/459 - (24%)
• Similarity: 202/459 - (44%)
• Gaps: 85/459 - (18%)

  Fly    85 YGDIFFMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHRE--EYRKDFYQGVMGVI 147
            ||..|.. .|:|. ..:.|.:.|.||.:.          .:.|||...:  ||.:.|...  |::
  Fly    67 YGKTFRF-WILGE-SLIYTKDLQYFETIL----------SSTTLLEKGQLYEYLRPFLND--GLL 117

  Fly   148 PTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWT 212
            .:.|:.|...|.:.... ...|.:..|.:.|.:.:...|..:.::.|..|.      :|     .
  Fly   118 VSTGRKWHARRKIFTHA-FHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTA------VD-----M 170

  Fly   213 LESVSVVALD----KQLGLLKNSNKESE-----ALKLFHYL--DEFFIVSIDLEMKPSPWRY-IK 265
            |:.||:.|||    ..:|:..|:..:.:     |||...|:  |..|..|     :...|.: :.
  Fly   171 LKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFS-----RRYNWLFPLA 230

  Fly   266 TPKLKR-LMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRP----------ENEQSVLEKLLK-- 317
            .|.|.| |:..:..:.:.|...:.|..|.:.:...:|..||          :::.::|:.||:
  Fly   231 APLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSS 295

  Fly   318 ----------VDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVL-PNKN 371
                      :..:|.|.|     ..|.|||||..:..|..:|::||.|.|:.||:.:|| |:.:
  Fly   296 INNQPLSDADIREEVDTFM-----FEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDAS 355

  Fly   372 SEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEY 436
            :..|:|.::::.||...|||:.||:|.:....|...::..:....:||.|.:.:|...|.....|
  Fly   356 APVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANY 420

  Fly   437 FPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIR 501
            ||....|.|||:|   :|.|        :..|.|.::||..||:.|:|::...:|:::..::::|
  Fly   421 FPDPLSFRPERFL---EDQE--------QGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLR 474

  Fly   502 NFNV 505
            .:.:
  Fly   475 FYEL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	111/459 (24%)
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	110/458 (24%)