Protein Alignment Cyp12a4 and Cyp4ad1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 432
• Identity: 96/432 - (22%)
• Similarity: 181/432 - (41%)
• Gaps: 67/432 - (15%)

  Fly   100 FLSTH----NPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVM--GVIPTQGKPWGDFR 158
            ||..|    :|.:.:.:..:.          :|||  :|:...|.:..:  |::.:.|..|...:
  Fly    78 FLQYHMMLSDPAEIQNILSSS----------SLLY--KEHLYSFLRPWLGDGLLTSSGARWLKHQ 130

  Fly   159 TVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDT---INRWTLESVSVVA 220
            .:..|. .:...:..|.:.:.:...:|||::      |.|....:..|.   :.:.||:.|...|
  Fly   131 KLYAPA-FERSAIEGYLRVVHRTGGQFVQKL------DVLSDTQEVFDAQELVAKCTLDIVCENA 188

  Fly   221 LDKQLGLLKNSNKESE-ALK-LFHYLDE--FFIVS-IDLEMKPSPWRYIKTPKLKRLMRA-LDGI 279
            ..:....|.....:.. |:| |...:.|  |.||. .|...:.:.: |:|..:...|:|: |:.|
  Fly   189 TGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSY-YMKQRRALSLLRSELNRI 252

  Fly   280 QEVTLAYVDEAIERLDKE--AKEGVVRPENEQSVLEKLL--KVDRKVATVMAM-----DMLMAGV 335
                   :.:...:|..|  .::|  :|.| :..|:.||  |:|.||.....:     ..:..|.
  Fly   253 -------ISQRRHQLAAENTCQQG--QPIN-KPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGH 307

  Fly   336 DTTSSTFTALLLCLAKNPEKQARLREEVMKVL-PNKNSEFTEASMKNVPYLRACIKESQRLHPLI 399
            |..::..:..|..|:::.|.|.:..||..::. .|...|...|.:..:.||...|:|:.||:|.:
  Fly   308 DPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSV 372

  Fly   400 VGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDE-YFPQASEFLPERWLRSPKDSESKCPANE 463
            ...||.......::|.:|...|.| |:.|.|:..:| ||.....|.|||:         :.|...
  Fly   373 PLIARTNRNPIDINGTKVAKCTTV-IMCLIAMGYNEKYFDDPCTFRPERF---------ENPTGN 427

  Fly   464 LKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV 505
            : ....|..:||..|||.|:.::....:::...::|:|.|.:
  Fly   428 V-GIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEI 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	96/432 (22%)
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	96/432 (22%)