Protein Alignment Cyp12a4 and npp-24

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001379685.1
• Gene: npp-24 / 3564830
• WormBaseID: WBGene00022672
• Length: 655
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 80/427 - (18%)
• Similarity: 139/427 - (32%)
• Gaps: 143/427 - (33%)

  Fly   100 FLSTHNPQDFEVVFRNEG--------VWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGK---- 152
            ::.|.||:...|.....|        |:||..|.:..|. :::.|.....|...::..|.:
 Worm   255 YIQTTNPRICSVFVLVSGGGVLSHLVVFPNEFGEFRFLV-KDQLRLPSSNGDPRIVQNQIRSLKV 318

  Fly   153 -----------------PWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEA 200
                             ||.:..|.::|.....|..|:         .|.|..::
 Worm   319 SRYEIATSSSLFSVNIFPWFEALTSISPTSTLEKETRV---------SELVDAVI---------- 364

  Fly   201 PDDFIDTINRWT----LESVSV-----VALDKQ---------LGLLKNSNKESEALKLFHYLDEF 247
            |.|.:....:||    |.:|||     :|.:::         :.|:...||:.:...||:
 Worm   365 PSDELSNTTKWTGARALRAVSVQLTQSLATEEEELLPESENIMHLVILENKDGQPAHLFN----- 424

  Fly   248 FIVSID----LEMKPS---------PWRYIKTPKLKRLMRALDGIQ--------------EVTLA 285
             |.:.|    .|.|.|         |.:  .|..|::.:.||..:.              :..:.
 Worm   425 -ISTFDNIWSTENKTSFGRDSVSQPPMK--STGSLEQQLAALKPLAACVISEKVSCEEAIDAAMK 486

  Fly   286 YVDEAIERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLA 350
            :.|...|||.|..       |..:..:|:.|.|.   ::..|:|.....||
 Worm   487 FFDAVDERLKKHC-------EISKLFVERCLAVS---SSAQALDEKQQSVD-------------- 527

  Fly   351 KNPEKQARLREEV-----MKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDA 410
                  .||.||.     :|:..::..|..|.:.|.:..|...:.|:.   ||.....|:..|
 Worm   528 ------QRLIEETNTVEELKIRMHETKERMEGARKGINVLFHRVDENV---PLSDNEIRIFER-- 581

  Fly   411 VLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPER 447
             |..::........:||...|..:|....|:..|.:|
 Worm   582 -LKEHQKMLSDMTKLVPKMTLDSNEIHRMANIVLKKR 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	80/427 (19%)
npp-24	NP_001379685.1	Nup88	26..>212	CDD:401976
		Smc	<455..>653	CDD:224117	38/199 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900