Protein Alignment Cyp12a4 and Cyp6a2

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 427
• Identity: 116/427 - (27%)
• Similarity: 183/427 - (42%)
• Gaps: 76/427 - (17%)

  Fly   136 RKDFYQG-----VMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDP 195
            |..|:.|     ...:....||.|.|.|..:.|.....| ::..:..:.:|::|||:.|.|....
  Fly   103 RGQFHNGRDDPLTQHLFNLDGKKWKDMRQRLTPTFTSGK-MKFMFPTVIKVSEEFVKVITEQVPA 166

  Fly   196 DTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKN--SNKESEALKLF----H-YLDEFFIVSID 253
            ....|..:..:.:.|:|.:.:...|...:...|:.  |:..:...|:|    | .|...|:.|.
  Fly   167 AQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSF- 230

  Fly   254 LEMKPSPWRYIKTPKL-KRL-MRAL-DGIQEVTLAYVDEAIERLDKE--------------AKEG 301
                         ||| .|| ||.: :.:.:..:..|::.|...::|              .::|
  Fly   231 -------------PKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKG 282

  Fly   302 VVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKV 366
            .|..:|.: |:|. :.:....|.|..  ..:||.:|:|||.:..|..||:|.:.|.|||.|:..|
  Fly   283 RVTLDNGE-VIEG-MDIGELAAQVFV--FYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTV 343

  Fly   367 LPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYR---VPAGTYVNIVPL 428
            |..:..:.|..|:|.:.||...|.|:.||:.|:....|....|.|:.|:.   :..||.| |:|.
  Fly   344 LEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQV-IIPA 407

  Fly   429 NALTRDE-YFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMEL 492
            .|..||| .:|....|.|||:      |..|..|.|     ...:||||.|||.|:|.|..:|:.
  Fly   408 CAYHRDEDLYPNPETFDPERF------SPEKVAARE-----SVEWLPFGDGPRNCIGMRFGQMQA 461

  Fly   493 ELGTARLIRNFNVEFNYPTENAFRSALINLPNIPLKF 529
            .:|.|::|..|.|.....||            ||||:
  Fly   462 RIGLAQIISRFRVSVCDTTE------------IPLKY 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	114/424 (27%)
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	116/427 (27%)