Protein Alignment Cyp12a4 and Cyp4ac3

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 129/574 - (22%)
• Similarity: 241/574 - (41%)
• Gaps: 136/574 - (23%)

  Fly     8 LSLIQSQKATLSLATQKRWQTNVATAEAREDSEWLQAKPFEQIPRLNMWALSMKMSMPGGKYK-- 70
            |.|.|..|....|:..||    |.||    |...|::|.| .:|               ||.:
  Fly    17 LLLRQLNKTYFILSLCKR----VRTA----DGSPLESKVF-VVP---------------GKTRFG 57

  Fly    71 -NMELMEM-----FEAMR--------QDYGDIFFMPGIMGNPPFLSTHN---PQDFEVVFRNEGV 118
             |::|:.:     |..:|        |:|         :.|..|...:|   .:|.|.:|::..:
  Fly    58 NNLDLLNLTPANIFSYIRESTAKANGQNY---------IWNFLFAPEYNIVRAEDAEEIFQSTKI 113

  Fly   119 WPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPV----LMQPKNVRLYYKKMS 179
             ..:..:|.|:   ..:..|      |::.:..:.|...|..:.|.    ::|.     :.....
  Fly   114 -TTKNMSYELI---RPFLGD------GLLISIDQKWHTRRKTLTPAFHFNILQS-----FLSIFK 163

  Fly   180 QVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKESEALKLFH-- 242
            :.:::|: :||:......||    ....|.::||.::...||..:|..:...|:..:|:..|.
  Fly   164 EESKKFI-KILDKNVGFELE----LNQIIPQFTLNNICETALGVKLDDMSEGNEYRKAIHDFEIV 223

  Fly   243 ----------YLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDG-----IQEVTLAYVDEAIE 292
                      :.:.:|.:..|.:            |..|::|.:.|     ||.....:..:.:.
  Fly   224 FNQRMCNPLMFFNWYFFLFGDYK------------KYSRILRTIHGFSSGIIQRKRQQFKQKQLG 276

  Fly   293 RLDKEAKEGVVRPENEQSVLEKLL------KVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAK 351
            ::|:..|      :...::|:.||      |:|.:.........:..|.||||::....||.||.
  Fly   277 QVDEFGK------KQRYAMLDTLLAAEAEGKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLAL 335

  Fly   352 NPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPL--IVGNARVLARDAVLSG 414
            :.:.|.|..|| ::.||....|.:......:.:|...||||.||.|.  |:|  |....::|::|
  Fly   336 HADVQERCYEE-LQDLPEDIDEVSMFQFNELIHLECVIKESLRLFPSAPIIG--RTCIEESVMNG 397

  Fly   415 YRVPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGP 479
            ..:|....::|...:.:....:||:.::|||||:|  |::|.::         :||.|:||..||
  Fly   398 LVLPKNAQISIHIYDIMRDARHFPKPNQFLPERFL--PENSVNR---------HPFAFVPFSAGP 451

  Fly   480 RMCVGKRIVEMELELGTARLIRNFNVEFNYPTEN-AFRSALI--NLPNIPLKFK 530
            |.|:|::...:|:::..|.:||||.:......|: .|.:.::  ...||.:||:
  Fly   452 RNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQQNIKVKFE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	107/488 (22%)
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	104/466 (22%)