Protein Alignment Cyp12a4 and Cyp318a1

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 128/571 - (22%)
• Similarity: 211/571 - (36%)
• Gaps: 145/571 - (25%)

  Fly    41 WLQAKPFEQIPRLNMW-------ALSMKMSMPGGKYKNMELMEMFEAMRQDYGDIFFMP--GIMG 96
            |.|.|.:..|.:||.|       .|.:.:.:      |:....:.|.:.| |...|..|  .::|
  Fly    20 WQQRKCWRLIWQLNGWRGVIQQPVLWLLLCI------NLHPNSILEKVSQ-YRVHFQRPLAVLVG 77

  Fly    97 NPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVM----GVIPTQGKPWGDF 157
            ....|...:|...|.|.       |.|         |...|.|.|...    |::..:|:.|...
  Fly    78 TRVLLYIDDPAGMECVL-------NAP---------ECLDKTFLQDGFFVRRGLLHARGQKWKLR 126

  Fly   158 RTVVNPVLMQPKNVRLYYKKMSQVNQEFVQR------------------------ILELRDPDTL 198
            |..:||.... ..|..::...:.|..:.|::                        :||:.....:
  Fly   127 RKQLNPAFSH-NIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSCLTIM 190

  Fly   199 EAPDDFIDTINRWTLES------VSVVALDK---QLGLLKN---SNKESEALKLFHYLDEFFIVS 251
            ..|.:|....:.....|      :|.|.:.|   |:.||..   .....|:.|....|::|  |.
  Fly   191 GTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAPELYEESKKCAKLLEDF--VG 253

  Fly   252 IDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVR----------PE 306
            ..:..|...|         ||..|:.|             |:..::|..|..|          ..
  Fly   254 GIVRTKHRNW---------RLRDAVGG-------------EKSGEDASNGWQRRIFIEQIFQLAA 296

  Fly   307 NEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNP-EKQARLREEVMKVLPNK 370
            |.:..||:::.        .|..|::...:|.|::....|||||.|. :.|.||..|:..::|:.
  Fly   297 NGEMTLEEIMD--------EAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDV 353

  Fly   371 NSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALT--- 432
            .....| .::.:.||.|.:.||.||...:..|.|.::||     :|:....:..|||.|::.
  Fly   354 GQVGLE-QLQQLRYLDAFVSESLRLLATVPMNLRHVSRD-----FRLAGRQHETIVPQNSIVVLD 412

  Fly   433 -----RDE--YFPQASEFLPERWL--------RSPKDSESKCPANELKSTNPFVFLPFGFGPRMC 482
                 |||  :...|.:|.|:|:|        :...||.|.....:....:.:.||||..|.|.|
  Fly   413 TFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSC 477

  Fly   483 VGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALINLPNIPLKFKFID 533
            :|:|.....:::...:||.||:.:.::..|.     |..:.||.||||..|
  Fly   478 IGRRYGLFIMKVFLVKLITNFDFQSDFELEK-----LQFVENISLKFKNAD 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	113/516 (22%)
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	115/515 (22%)