Protein Alignment Cyp12a4 and cyp-35B2

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_504094.1
• Gene: cyp-35B2 / 187093
• WormBaseID: WBGene00019471
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 131/540 - (24%)
• Similarity: 225/540 - (41%)
• Gaps: 107/540 - (19%)

  Fly    41 WLQAKPFEQIPRLNMWALSMKM--SMPGGKY---KNMELMEMFEAMRQDYGDIFFMPGIMGNPPF 100
            :|.|:.:::..:|....:|:.:  ::|...|   :...::..|:..||.|||:|.:  .:|..|.
 Worm    13 FLVARQYQKAKKLPPGPVSLPLIGNIPQLVYYIWREKGVVPAFDLFRQIYGDVFTI--WLGPIPH 75

  Fly   101 LSTHNPQDFEVVFRNEG----------VWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWG 155
            :|..:....:.||...|          |:.:...|                  :|::...|:.|.
 Worm    76 VSICDYDTSQEVFVKNGSRLIDRFLPPVFLHLSNN------------------LGLVSANGEVWA 122

  Fly   156 DFRTVVNPVLMQPKNVRLYYKKMSQ-VNQEFVQRILELRDPD-----TLEAPDDFIDTINRWTLE 214
            :.|..   .|:..:|:.:....|.: :.:|...|..|: |.|     |:....||.|.
 Worm   123 EMRRF---TLLAFRNIGVGRDSMEERILEELDARCEEI-DADAVNGKTVVQTSDFFDL------- 176

  Fly   215 SVSVVALDKQLGLLKNSNKESEALKLFHYLD---EFFIVSIDLEMKPSPWRYIKTPKLKRLMRAL 276
            :|..:..:..:|...|::.:.|.:||...:|   :.|.: .||   .:|...:|....||..|.|
 Worm   177 AVGSIINNTLIGKRFNAHNKDEFMKLKKMMDSASDLFTI-FDL---TAPVWMLKILVPKRCERIL 237

  Fly   277 DGIQEVTLAYVD-EAIERLDK-EAKEGVVRPENEQSVLE----KLLKVDR---------KVATVM 326
             |:||..|.:|. ||.||.:: ::.|..|..||....:|    |:.:..|         |....:
 Worm   238 -GVQEEILNFVSREANERYEQLKSGEYTVNAENPHDFVEAYFAKMEEEKRHGGPTPYTMKCLKHV 301

  Fly   327 AMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKE 391
            ..|:.:||.|||::|..:....|..:||...:.|||::::..|.:............||.|.|.|
 Worm   302 IGDLWLAGQDTTTTTLVSGFNQLVNHPEVIRKCREEILRITENGSRPLQLKDRAESHYLNATITE 366

  Fly   392 SQRLHPLI--VGNARVLARDAVLSGYRVPAGTYVNIVPLNAL-TRDEYFPQASEFLPERWLRSPK 453
            .|| |..|  |...|::.....:.||.:.:|| |....|.|| ..::.|..|.:|.|||::.:.|
 Worm   367 IQR-HASILNVNFWRLINEPTNVKGYEIDSGT-VMTAQLGALHVNNDIFKNADKFYPERFIENGK 429

  Fly   454 DSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSA 518
                  ..|::        :|||.|.|.|||:.:...||.|.|..|:..:|:.    ...:..|.
 Worm   430 ------LLNQV--------IPFGIGKRSCVGENLARSELYLLTGNLLLRYNIR----PHGSLPST 476

  Fly   519 LINLP---------NIPLKF 529
            ...||         |:.|:|
 Worm   477 ADQLPYSAGKMPDKNVHLEF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	125/504 (25%)
cyp-35B2	NP_504094.1	p450	26..453	CDD:278495	116/478 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D574756at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010