Protein Alignment Cyp12a4 and cyp-33D1

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_507076.1
• Gene: cyp-33D1 / 187025
• WormBaseID: WBGene00010589
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 504
• Identity: 126/504 - (25%)
• Similarity: 205/504 - (40%)
• Gaps: 111/504 - (22%)

  Fly    76 EMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQDFEVVFRNEG-VWPNRPGNYTLLYHREEYRKDF 139
            ::|...::::|.:|..  .:.:.||:...:.:..:..|..:| .:.::..|        :..|..
 Worm    47 DIFHKWKKEFGPVFTF--WLADRPFIFITSYEVMKETFVKDGDTFADKQLN--------QIDKKK 101

  Fly   140 YQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDF 204
            .|...||:.|.|:.|.:.|..   .|.|.:::.| .|.:.|      ::||       ||..:.|
 Worm   102 LQRNYGVLDTNGEMWREHRRF---TLSQLRDLGL-GKDLMQ------EKIL-------LEIEEQF 149

  Fly   205 IDTINRWTLESVSVVA-LDKQLG-----LLKNSNKESEALKLFHYL-----------DEF----- 247
            .| ||....|.:.:.: ||:.:|     .|.|...|:.....|.||           .||
 Worm   150 KD-INSHLGEEIDLPSVLDRGVGNVINLTLFNKRFETNQRDEFTYLKSLIDGLRDVASEFRYFIQ 213

  Fly   248 FIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPENEQSVL 312
            |:|....::.|.|....||..:|         :|:.:.:|.: :|...||.....|   .....:
 Worm   214 FLVPWSSKIIPGPTLGDKTKGMK---------EELDVFFVKQ-VEEHRKEIDFDTV---ESYDYV 265

  Fly   313 EKLLKVDRKVAT-------------VMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVM 364
            |..||..:|...             .|..|:.|||:.||:.|.|........|.:.|.::|||:.
 Worm   266 EAYLKEQKKREADGDHETFCNKQLYAMCFDLWMAGLQTTTVTLTWGFSFYLHNADVQLKIREELD 330

  Fly   365 KVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGN-ARVLARDAVLSGYRVPAGTYVNIVPL 428
            :|:.| :...|.|....:|||.|.|.|:||...:|..| ..|..||.|:.||.|..||.| |..:
 Worm   331 RVIGN-DRLITTADKNCLPYLTAFINETQRCANIIPFNLLHVATRDTVIEGYPVKKGTGV-IAQI 393

  Fly   429 NALTRDE-YFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMEL 492
            ..:..|| .||.|..|.|.|::.:.|          ||..:..:  ||..|.|.|:|:.:..|||
 Worm   394 GTVMSDEQIFPDAHCFNPGRFIENGK----------LKKVDEVI--PFSIGKRQCLGEGLARMEL 446

  Fly   493 ELGTARLIRNFNVEFNYPTENAFRSALINLPNI---------PLKFKFI 532
            .|..|.:...::|:.::..         |||::         |.||..:
 Worm   447 FLFFANIFNRYDVQLDFSG---------NLPDLDKSKDNFVTPRKFNAV 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	126/501 (25%)
cyp-33D1	NP_507076.1	p450	26..482	CDD:278495	124/498 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4812
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950