Protein Alignment Cyp12a4 and sad

DIOPT Version :10

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_310837.6
• Gene: sad / 1271975
• VectorBaseID: AGAMI1_008403
• Length: 501
• Species: Anopheles gambiae
• Alignment Length: 524
• Identity: 109/524 - (20%)
• Similarity: 209/524 - (39%)
• Gaps: 112/524 - (21%)

  Fly    44 AKPF------EQIPRLNMWALSMKMSMPGGKYKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLS 102
            ||||      .:||.|.|....|::..|.      ||........:.|||:..:.  :|....:.
Mosquito    31 AKPFAEMPGPRRIPLLGMLNDVMQLGKPA------ELHLRISKYHEQYGDLVRLQ--IGTQNAVF 87

  Fly   103 THNPQDFEVVFRNEGVWPNR--PGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVN-PV 164
            ..:|......|:.||.:|..  |.::|....:.:|::       |:....||.|...|.:.| |:
Mosquito    88 VRDPSLMRKTFQLEGAYPRHPLPESWTYFNKKHDYQR-------GLFFMDGKEWLQSRQIFNKPM 145

  Fly   165 LMQPKNVRLYYKKMSQVNQEFVQRILELRDP----DTLEAPDDFIDTINRWTLESVSVVALDKQL 225
            |   |:.....:.:....:..|..:.:..|.    :.:||      .:.:|::|    |.|...|
Mosquito   146 L---KDFHWMEEPIRGTCEATVGHMQQTCDSAAAFEGIEA------FLYQWSVE----VVLSVML 197

  Fly   226 GLLKNSNKESEALKLFHYLDEFFIVSIDL----------------EMKPSPWRYIK--TPKLKRL 272
            |......::|...:  ..:.:|..|..|:                .:...||:..:  .|:..||
Mosquito   198 GSAFTECQQSAEFR--RLVQQFSAVVYDIFRCSSELMNIPPAIADRLNVQPWQQFEKVVPETIRL 260

  Fly   273 MRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLL-KVDRKVATVMAMDMLMAGVD 336
            ..|:                     .:.|:...:....:|:.:: |:|:.:...:.:|.::|..|
Mosquito   261 ATAI---------------------IEFGIANAQTRDGLLDLMMQKLDKPLMMRIFIDFIIAAGD 304

  Fly   337 TTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVG 401
            ||:......|..||.|...|..:|::|:      :|...|...     ::..::|:.||:|:...
Mosquito   305 TTAFATVWALYLLASNANLQQSVRQDVL------DSNTLECGA-----VKGVVRETLRLYPIAPF 358

  Fly   402 NARVLARDAVLSGYRVPAGTYVNIVPLNALTRDE-YFPQASEFLPERWLRSPKDSESKCPANELK 465
            ..|.:..::|...|.:|..|.| ::.|.:..||| :|.:...|.|.||.|:          |..:
Mosquito   359 IGRFVEHESVFGAYALPKDTLV-LLSLYSAGRDERFFAEPEAFNPYRWQRT----------NAAE 412

  Fly   466 ST---NPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEF-NYPTENAFRSAL--INLPN 524
            |:   .|...|||..|.|.|:|::|.::::....:.::..|::.. ....::|.:..|  |.:|:
Mosquito   413 SSTGRTPSASLPFAIGARSCIGQKIAQLQMHYLLSMILTKFDLTLAEADQQDAIKPILKMITVPS 477

  Fly   525 IPLK 528
            .|:|
Mosquito   478 APVK 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	96/478 (20%)
sad	XP_310837.6	None