Protein Alignment Cyp12a4 and cyp26c1

DIOPT Version :9

• Sequence 1: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 693
• Identity: 128/693 - (18%)
• Similarity: 219/693 - (31%)
• Gaps: 285/693 - (41%)

  Fly     6 SALSLIQSQKATLSLATQKRWQTNVATAEAREDSEWLQAKPFEQIPRLNM-WAL---SMKMSMPG 66
            |||||:     .|..|:.:.|.....:...|..|        ..:|:.:| |..   ::...:.|
 Frog    18 SALSLV-----LLLAASHQLWSLRWHSTRDRGSS--------LPLPKGSMGWPFFGETLHWLVQG 69

  Fly    67 GKYKNMELMEMFEAMRQDYGDIF--FMPG---------------IMGNPPFLSTHNPQDFEVVFR 114
            ..:.:        :.|:.||:||  .:.|               ::|....:||..||..:::.
 Frog    70 SSFHS--------SRREKYGNIFKTHLLGKPVIRVTGAENIRKILLGEHHLVSTQWPQSTQIIL- 125

  Fly   115 NEGVWPNRPGNYTLL-----YHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLY 174
                     |:.||.     .||::                       |.:::.||
 Frog   126 ---------GSNTLSNSIGELHRQK-----------------------RKMMSKVL--------- 149

  Fly   175 YKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLES-------VSVVALDKQ-------- 224
               .|...:.::.||.|                ..||.:.|       ||:::..|.
 Frog   150 ---SSAALESYLPRIHE----------------AVRWEVRSWCRGVGPVSMLSCAKALTFRIAAR 195

  Fly   225 --LGLLKNSNKESEALKLFHYL-DEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAY 286
              |||.....:..|..:.|..| :..|.:.:|:...          .|::.|:|.|.:.:    |
 Frog   196 ILLGLSLTDTQFQELTRTFEQLVENLFCLPLDIPFS----------GLRKGMKARDTLHQ----Y 246

  Fly   287 VDEAI-ERLDK---------------EAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGV 335
            ::||| |:|.|               .|||| .:..|.|.:.|.            |::::.|..
 Frog   247 MEEAIKEKLSKRDPDACEDALDYLINSAKEG-GKEINMQELKES------------AIELIFAAF 298

  Fly   336 DTTSSTFTALLLCLAKNPEKQARLREEV------------------------------------- 363
            .||:|..|:|:|.|.|:|....::|:|:
 Frog   299 LTTASASTSLVLLLLKHPSAIHKIRQELASHGLSEHCEQCLPATENPNNNILQDNGHQCLTAGCQ 363

  Fly   364 -----------------------------------MKVLPNKNSEFTEA---------------- 377
                                               .|.|.|..:...||
 Frog   364 LPLVMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSSKNLVNGENRIQEAPCSHDKSNCSPVPGKL 428

  Fly   378 ----------------SMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIV 426
                            .:|::.||...:||..||.|.:.|..|...:...|.||::|.|..|...
 Frog   429 QNSVFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLPPVSGGYRTALQTFELDGYQIPKGWSVMYS 493

  Fly   427 PLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEME 491
            ..:.......:..|..|.|||:  |.:..|.|        ...|.::|||.|.|.|:||.:.::.
 Frog   494 IRDTHETAAVYQNAEMFDPERF--STERDEGK--------LGRFNYIPFGGGARSCIGKELAQII 548

  Fly   492 LELGTARLIRNFNVEFNYPTENAFRSALINLP--NIPLKFKFI 532
            |::....|:.....|...|:....::..:..|  .:.|.|.|:
 Frog   549 LKILAMELVTTAKWELATPSFPKMQTVPVVHPVDGLQLSFSFL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	113/620 (18%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:425388	113/634 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D574756at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010