DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp12a5 and CYP86A8

DIOPT Version :9

Sequence 1:	NP_650782.1	Gene:	Cyp12a5 / 42293	FlyBaseID:	FBgn0038680	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_182121.1	Gene:	CYP86A8 / 819205	AraportID:	AT2G45970	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	117/487 - (24%)
Similarity:	208/487 - (42%)	Gaps:	92/487 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ALPGGKYKNLEMME--MIDALRQDYGN----IIFLPGMMGRDGLV-MTHNPKDFEVVFRNE-GVW 119
            :|| |..:|.|.|.  :.|.||...|.    |..:|.:..:.||| :|.:|::.|.:.:|. ..:
plant    38 SLP-GLIENCERMHDWISDNLRACSGTYQTCICAIPFLAKKQGLVTVTCDPRNLEHILKNRFDNY 101

  Fly   120 PFRPGSDILRYHRTVYRKDFFDGV-QGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYF--KKMSQV 181
            |..|          .::..|.|.: |||..|.|.:|          |.|.|...|.|  :.:.|.
plant   102 PKGP----------TWQAVFHDLLGQGIFNSDGDTW----------LFQRKTAALEFTTRTLRQA 146

  Fly   182 NQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRES------GKNSEATKL 240
            ...:|....::|          ||..:....|.|..:...|..|.|..::      ||:......
plant   147 MARWVNRAIKLR----------FLPILENARLGSEPIDLQDLLLRLTFDNICGLTFGKDPRTCAP 201

  Fly   241 FKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTL--------KYVDEAIERLEKE 297
            ...::.|.: :.|...:.||.|:....:|.|..|.:....||:|        .|:.|.|...::|
plant   202 GLPVNTFAV-AFDRATEASLQRFILPEILWKFKRWLRLGLEVSLTRSLVQVDNYLSEIITTRKEE 265

  Fly   298 AKEGVVRPEHEQSVLEKLLK-----VDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQA 357
            ........:|...:|.:.:|     .|:.:..| |::.::||.||:|...:.....:.::|..:.
plant   266 MMTQHNNGKHHDDLLSRFIKKKESYSDETLQRV-ALNFILAGRDTSSVALSWFFWLITQHPAIED 329

  Fly   358 RLREEVMKVLPN---------KDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVI- 412
            ::..|:..||..         .|...:...:..:.:|:|.:.|:.|:||.|..:::...:|.|:
plant   330 KILREICTVLVETRGDDVALWTDEPLSCEELDRLVFLKAALSETLRLYPSVPEDSKRAVKDDVLP 394

  Fly   413 SGYRVPAGTIVSMIPINSLYSEEYFPKPT------EFLPERWLRNASDSAGKCPANDLKTKNPFV 471
            .|..||||:.::.    |:||.... |.|      ||.||||:  :....|:...:|     ||.
plant   395 DGTFVPAGSSITY----SIYSAGRM-KSTWGEDCLEFKPERWI--SQSDGGRFINHD-----PFK 447

  Fly   472 FLPFGFGPRMCVGKRIVEMELE-LGTARLIRN 502
            |:.|..|||:|:||.:..:::: :.:|.|:|:
plant   448 FVAFNAGPRICLGKDLAYLQMKSIASAVLLRH 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	110/467 (24%)
CYP86A8	NP_182121.1	CYP86A	67..503	CDD:410687	107/457 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000