DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp12a5 and CYP718

DIOPT Version :9

Sequence 1:	NP_650782.1	Gene:	Cyp12a5 / 42293	FlyBaseID:	FBgn0038680	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_181813.1	Gene:	CYP718 / 818885	AraportID:	AT2G42850	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	479	Identity:	101/479 - (21%)
Similarity:	184/479 - (38%)	Gaps:	103/479 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 RYHRTVYRKDFFDGVQGIIPSQ-GKSW-GD-------------FRSIVNPVLMQPKNV---RLYF 175
            ::||.:.:|  ....:.::|.: |..| |:             |...|||.:::..|:   |:..
plant    30 KHHRFITKK--IQKKKKLLPGEMGLPWIGETMDFYKAQKSNRVFEDFVNPRIIKHGNIFKTRIMG 92

  Fly   176 KKMSQVN----------QEFVELIKEIRDASTQEVPGNFL--------ETINRWTLESVSVVALD 222
            .....||          .||..::.....:|.|.:..|.:        ..:......|:|.:.|:
plant    93 SPTIVVNGAEANRLILSNEFSLVVSSWPSSSVQLMGMNCIMAKQGEKHRVLRGIVANSLSYIGLE 157

  Fly   223 ---------------------KQLGLLRESGKNSEATKLFKYLDEFFLHSADLEM-KPSLWRYFK 265
                                 :::.|.| |.|....|.:|:.|....:....||: :..|...|.
plant   158 SLIPKLCDTVKFHHETEWRGKEEISLYR-SAKVLTFTVVFECLYGIKVEIGMLEVFERVLEGVFA 221

  Fly   266 TPL---LKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHE--QSVLEKLLK---VDKKV 322
            .|:   ..|..|...:..|:....|.:..|:..:..|||..:|...  ..::|:|:|   .:::|
plant   222 LPVEFPCSKFARAKKARLEIETFLVGKVREKRREMEKEGAEKPNTTLFSRLVEELIKGVITEEEV 286

  Fly   323 ATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNK-DSEF-TEASMKNVPYL 385
            ...|.: ::.|..||||...:.....||::|..:..|.:|..::..|| :.|: |...:|.:.|.
plant   287 VDNMVL-LVFAAHDTTSYAMSMTFKMLAQHPTCRDTLLQEHAQIKANKGEGEYLTVEDVKKMKYS 350

  Fly   386 RACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEYFPKPTEFLPERWLR 450
            ...::|:.|:.|.:.|:.|....|....||.:|.|..:......:.|:.|.|..|..|.|.|:
plant   351 WQVVRETMRLSPPIFGSFRKAVADIDYGGYTIPKGWKILWTTYGTHYNPEIFQDPMSFDPTRF-- 413

  Fly   451 NASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAF 515
                        | |....:.:||||.|||:|.|.::.::.:            :.|.|.....|
plant   414 ------------D-KPIQAYTYLPFGGGPRLCAGHQLAKISI------------LVFMHFVVTGF 453

  Fly   516 RSALI----NLPNIPLKFKFTDVP 535
            ..:|:    .:...||.|....:|
plant   454 DWSLVYPDETISMDPLPFPSLGMP 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	100/473 (21%)
CYP718	NP_181813.1	CYP90-like	78..482	CDD:410669	90/429 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D574756at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010