Protein Alignment Cyp12a5 and cyp27a2

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_686522.4
• Gene: cyp27a2 / 558239
• ZFINID: ZDB-GENE-120215-110
• Length: 573
• Species: Danio rerio
• Alignment Length: 430
• Identity: 124/430 - (28%)
• Similarity: 208/430 - (48%)
• Gaps: 34/430 - (7%)

  Fly   112 VFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFK 176
            |.|.||.:|.|  :|:  .|...|| |......||....|..|...||.:||.:::.|.|..|..
Zfish   164 VIRQEGRYPVR--TDL--PHWREYR-DMRGQAYGIHVDTGPEWYRIRSALNPKMLKLKEVTAYAP 223

  Fly   177 KMSQVNQEFVELIKEIRDASTQEVP-GNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKL 240
            .:.:|..:.::.::.:|..|..::. .:....:.::..|.:|.:..:.:||.|:|. ..::..:.
Zfish   224 IIHEVVSDLLQRLELLRLRSPDQITVSDLASELYKFGFEGISSILFETRLGCLQEE-IPTDTLRF 287

  Fly   241 FKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRP 305
            ...::|....|..:...|. |.....|..|:.::..|.:.:|....:|:.:    .|.::.|.|.
Zfish   288 ISAVNEMLALSETVLFFPR-WTRHIFPFWKRFVQAWDELYDVARHLIDKKV----NEIRDQVARG 347

  Fly   306 EHEQSVLEKLLKVDKKVAT----VMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKV 366
            |..:.:....|....|::.    :...::|:.||||||:|.:..|..||:|||.|.||..|::.|
Zfish   348 EEVEGMYLTYLLSSNKLSLGEVYISLTELLLGGVDTTSNTLSWTLYHLARNPEIQKRLHNEIVSV 412

  Fly   367 LPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDS--VISGYRVPAGTIVSMIPIN 429
            .|||....|: .:..:||::|.|||..|:||:|.||.| ||.||  |:..|..|..|...:....
Zfish   413 CPNKKVPNTD-DLTKMPYMKAVIKEILRMYPVVPGNGR-LTVDSDIVVDNYWFPKKTQFHLCHYA 475

  Fly   430 SLYSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELEL 494
            ..:.|..||....|:||||:|   ||..:      ...:|:..:|||.|.|.|||||:.|:|:..
Zfish   476 VSHDENNFPDAERFVPERWIR---DSPSR------SQHHPYSSVPFGVGVRACVGKRVAELEMYF 531

  Fly   495 GTARLIRNFNVEF---NHSTKNAFRSALINLPNIPLKFKF 531
            ..:||::.:.|..   :.|.:...|:.||  |:.|:..:|
Zfish   532 ALSRLMQQYEVRTKAGSPSIQPKTRTLLI--PSQPIDLQF 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	123/425 (29%)
cyp27a2	XP_686522.4	cytochrome_P450	136..567	CDD:477761	123/426 (29%)