Protein Alignment Cyp12a5 and Cyp6a22

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 459
• Identity: 118/459 - (25%)
• Similarity: 198/459 - (43%)
• Gaps: 107/459 - (23%)

  Fly    71 NLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTVY 135
            :||:.:.|  |.||:.|.         :...|.||.:|                 |.|..|  ::
  Fly    85 DLELAKQI--LIQDFANF---------EDRGMYHNERD-----------------DPLTGH--LF 119

  Fly   136 RKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKEIRD---AST 197
            |.|            |..|...|..::|.....| ::..|..:.:|.:|..::..|:.|   ...
  Fly   120 RID------------GPKWRPLRQKMSPTFTSAK-MKYMFPTVCEVGEELTQVCGELADNAMCGI 171

  Fly   198 QEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEA------TKLF------KYLDEFFLH 250
            .|: |:.:.   |:|.:.:...|...:...||    |.||      .:.|      |.:|.|
  Fly   172 LEI-GDLMA---RYTSDVIGRCAFGVECNGLR----NPEAEFAIMGRRAFSERRHCKLVDGF--- 225

  Fly   251 SADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSVLEKL 315
               :|..|.:.|:         ||.....|::|..||....|.:::..::|:||.:....::|..
  Fly   226 ---IESFPEVARF---------LRMRQIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMK 278

  Fly   316 LKVDKKVATVMAMDMLM--AGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEAS 378
            .:.:..:..:.|...:.  ||.||::||....|..|||.|..||:||||:.:.|...:.|||..|
  Fly   279 QRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDS 343

  Fly   379 MKNVPYLRACIKESQRVYPLVIGNARGLTRDS----VISGYR---VPAGTIVSMIPINSLYSE-E 435
            |:.:.|:...|.|:.|.||::    ..|||.|    ...|.|   :..|.:: :||:..::.: .
  Fly   344 MQELRYMELVIAETLRKYPIL----PQLTRISRHLYAAKGDRHFYIEPGQML-LIPVYGIHHDPA 403

  Fly   436 YFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLI 500
            .:|:|.:|:|||:|           |:.|..:....:||||.|||.|:|.|..:|:..:|...|:
  Fly   404 LYPEPHKFIPERFL-----------ADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLL 457

  Fly   501 RNFN 504
            |||:
  Fly   458 RNFH 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	114/448 (25%)
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	118/459 (26%)